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Rosalie Apr 2013
Let me tell you what I've learned about toxicology
My life is toxic and I owe it an apology
Peer Pressure?
Whats that?
Like an invite to get ****** up with friends?
Oh, you should resist that?
I always remember once the night ends


But not much else
The flesh of your words are gangrene
Sloughing at the tips
Their inflection an infection
Necrosis apocalypse
Swelling reds and gorging purples
Lack of bloods life flow
Putrid rotting letters
Thrombosis runs the show
Losing membrane integrity
Their fetid smell does waft
Forced fed through the senses
Until we subjugate
I can tell by the smell
Under the perfume
The only thing that they will do
Is lure us to our tombs
So keep your words and parlor tricks
I see them clear as day
Countless ways to contaminate
And weaken all your prey
It's time to tie the tourniquets
At the shoulders and the thighs
The time is now to amputate
This toxicology of lies
You can tell their worth by counting all the swarming flies
Thinking of You Nov 2021
There’s been a lot of toxic love before you.
You being pure makes me see it.
Maia Vasconez Sep 2019
The weatherman said it was going to rain but he didn’t mention
when it would let up. It’s been raining for years.

I keep telling myself I’m not allowed to be this downpour,
this unhappy
all the time. It doesn’t help.

I don’t want to be brave today. I don’t
want to do the work today. I don’t want to do the work today. I don’t want
to do the work today. I don't want to.

The only thing worth living for is the sunset. I’m letting things
pile up instead of taking care of them. I want to see
how high I can get.

This is the terrible precipice I’ve been peering over.
Everyone/ no one is worried for me.
If I fall on them,
I will be so heavy. And what is it if it isn’t

everyone you take with you on the way down?
I thought I would fall right into the sunshine. I thought I’d be
covered in it.



Oh my god I can’t die yet,
my room isn’t clean.

Look, I brushed my hair.
I got dressed.

See, I'm better now. See?
Jonny Angel Jan 2014
You
were raised
on diesel fuel,
coal dust & corn liquor,
inhaled gnats by the ton.

I
want
you to spit in my mouth,
to taste your toxicology,
to absorb your proteins
& dirt.
Percocet
*******
Xanax
OxyNEO

And god knows what else.
You keep telling me “I’m not high I swear! I’m just tired”
But your lips are tinged blue, you have saliva in the creases of your mouth, your body is frail and sickly looking, your skin so white it’s almost transparent. Your eyes are swollen, glossy, and gaunt, your cheeks are sunken, your hair is tangled and unwashed.

“I’m not high I swear!”

But I don’t believe you. How many times have you said that to me only to confess later that you were, that you found a pill and didn’t have the self control not to take it.

“I’m not high I swear”

Yet you randomly smack your head, blurt out random words and nonsense, forget entire conversations, fall asleep mid sentence.

You said you were clean. But the very next day I get a call telling me that you’ve been arrested for a DUI, you had Xanax and Oxyneos in your toxicology report.

I’m afraid to answer my phone when it rings, I always fear it will be the call that tells me you’ve overdosed.

You said “I don’t need to go to rehab, I can quit myself”
But if that were true, you’d be clean by now. It’s been over a year since you told me you were addicted to pills.
At first it was just a perc or two, and now you are a full blown opioid abuser.

You’ve become the thing you hated most. An addict that can’t admit that they have a problem.

“Im not high I swear”

I can’t count how many times you’ve said that, how many times you lied to my face. So many times I never want to hear those words come out of your mouth again.
But I know I will, and I know I’ll go home and cry after and pray to god you wake up tomorrow.

I just want my best friend back, the kind and honest loving girl you use to be.
I’m tired of the you you’ve become.
The girl that lies, that steals, that is wasting away.

If only you never took that first pill.
Addiction steals everything.
Mateuš Conrad Nov 2017
get your ***** ******* grubs off of me,
i am not going to bargain
a cartesian dualism with the notion
that the body can overcome the mind
with exercise gimmicks:
you, *******, guinea nimwit!
        i used to slap my grandfather's
sheen on a bold, but otherwise
bald cranium for jokes,
  and flick his remaining hairs into
the air to reveal a hidden jack
nicholson, i also called the police
and had him institutionalised with
psychiatric aid, for throwing my
grandmother through a glass door and
breaking her arm...
       me?! you'll get more
apologetic "nuance" about drinking
from a priest than from, me!
         i turn ugly, silently,
       i just abhore this antique deal
with descartes,
               i don't know why why that
the body can overcome the mind...
or why blankety-blank trivia is to solve
the matter...
or whether pumping iron helps...
      by this point i''m not writing:
i'm coal-mining, i'm digging...
               the body, however perfect
will not unravel the problems of the mind,
attaining body antics perfected only
stalls the otherwise still present:
problems of the mind.
                       toxicology reports read:
adrenaline *****.
             sebastian mc'queer miss-match
between a cocktail waitress,
  a ******* bunny and a bartender named:
shteeve.
                 ******* waste of time
by my rubric of arithmetic...
  but at least ben affleck wasn't the worst
batman,
      we all know that george clooney was.
we have finally arrived at a loss
of mind-body dualism,
   we have achieved a dichotomy,
finally!
       we can, for the first time,
fathom clear segregating posits,
indicators,
                    membranes!
whatever noun you use -
                 the joke about schizophrenia,
is that it's not a joke concerning
        premature depression -
premature depression is more unusual
than premature dementia -
      there's the bicimeral theory
to begin with...
           unless of course you're dealing
with snowflakes who want languaage
as rigid as possible,
      readied for the acceptance of it,
like any type of i.k.e.a. put it together,
yourself, manual...
the mundane aspect of the whole affair
only breeds a gagging effect,
like choking on a 12" **** with your nose
pinched-shut,
  ******* disgusting;
  if i really wanted to draw a straight line
i wouldn't necessarily obligate language
to latex ******* *******...
           i'd be the one
adding oil to the fire, and wanting
unadulterated chaos,
  before the hell-fire focus of: inferno...
for language is just that:
   i abhor the term poet,
i prefer the term...
                               pyrotechnician...
i do not write poetry:
   i cement myself in pyrotechnics.
    i abhor this dualism -
            this notion that a sick mind can
be mended by being worked on by
a invigorated body,
      or that a sick body can be mended by
being worked on by an
invigorated mind...
   odd... to have such vehement emotions
surrounds a mere idea...
that there is no mind-body dualism,
but that there's a mind-body dichotomy...
and that there's only a mind-mind dualism
that, given the cartesian concept brideges
upon the res extensa: the extended thing,
whereby the mind-mind dualism
disintegrates when the notion of a, soul,
is involved / invested in,
perhaps as concrete rubric, or perhaps
as a mere cognitive, hobby...
  let us simply add:
   there are those who bow and pray and
pay due diligence to a god...
  while others, neither procrastinate themselves,
nor day allegiance to a, deity -
for there is so much more involvement in
entertaining the thought of a...
deity...
             and these cognitive
acrobatics never allow for a yawn
to be present, in their ritualistic endeavours,
with due need, or due, cause.

p.s. i think people really underestimate
schizophrenics, the abnormality of it
is fascinating...
      as is the case with the endeavour of
finding a soul, or as i like to call it:
the osmosis of psyche overpowering the mind,
and creating a mind-body dichotomy
rather than enforcing a mind-body "dualism"...
psychosis.
                   it's a shame how people
under-appreciate a mind-mind dualism...
a dualism, split, yet nonetheless whole...
     cf. julian jaynes...
                      but what isn't fascinating
is premature depression...
   that's just plain ******* tragic...
i can understand depression in old people,
who have actually accomplished something
in their lives...
but when it concerns youngsters?
completely unfathomable and
                    uninteresting to me,
on the basis that it's so abnormal that
it's suicidal and completely averted to
the otherwise schizoid exploratory tendency
of reintegrating a disintegrating form
of language structure... perhaps that's
a post-modernist statement...
but the "sane" always cite
being perplexed by language that's:
   non-instructive; b'aah b'aah...
******* herds, do we always have to whip
them into submission and cohort?
  yes, yes, the open end hyphen grammar
   -cohort-, that's transcendental grammar,
it's not supposed to be a noun,
rather, an adjective by-and-of-itself
revealing of the submissive character of
strict, military, discipline!
my ambition was never to write
a ******* i.k.e.a. manual for a: do it yourself
take on a folding chair!
69%
the beast howls the serpents home
sends fire up the spine of anyone
dare enough to be brave and dare me
terror amplified by the terror it tried
to feed me,  a dish of my own tongue
proper etiquette my mouth is mutual

hand gun presently displayed at his funeral
open casket hide the wound he was shooting from
at open lung hide this toxicity toxicology talk
st peter knows opiates like i know opiates
Mieux nous mentir nus ensemble et rester au chaud, puis être vêtu dans la tombe et être froid mais toujours aimante, en enfer , dans sa chaleur et les flammes nues . vous êtes mon tout, vous êtes mes se dévisse, mon prophète de l'amour, c'est pas mal cupidon
Vivekanshu Verma Apr 2020
Riddle in Rhymes,
During Corona Times
By Toxic Detective for Indian Society of Toxicology (IST)
Vomiting is nature's protective reflex against ingested toxins with my bitter alkaloids, accidental by innocent kids,
Bitter is Killer 💀, As a thumb's #rule, in medical science; but most of life saving medications are also bitter 👅, instead;
Vomiting after ingesting me, protects you medically as well as legally, in court of law leads;
Prehistoric #judicial systems determined guilt or innocence in a legal #trial, for human misdeeds;
By subjecting the accused to a dangerous experience, traditionally known as “trial by #ordeal” misusing my seeds;
Whether one survived such an ordeal poison of mine,
was left to control of divine,
to be freed;
and escape or survival was taken to indicate innocence on behalf of the defendant, instead;
The roots of this custom lie in the Code of #Hammurabi and the Code of Ur-Nammu, the oldest known systems of law, reads;
Numerous West African tribes from #Calabar, depended on my toxic bean in jurisprudence, in needs;
Also renowned as ordeal poison or #lie-detector bean, for rulings in their early courts, impledes;
Tribal #Nigerians, misused toxic action of my beans to detect witches & people possessed by evil spirits, who concedes;
#Judicators, would feed numerous seeds, what they called “ordeal poison,” to the accused; if he or she was innocent, indeed;
Hypothetically, God would perform a miracle and allow the accused to live—and the court would have its ruling, proceeds;
If the reverse was true, of course, guilt would be “proven” the moment its sentence was successfully carried out, in recede;
I am a climbing leguminous plant in forests, can be poisonous to humans when chewed, as beads;
I am a large, herbaceous perennial vine, with a woody stem at the base, as natural weeds;
I produces a large, purplish flower with intricate visible veins; attracting innocent Kids;
My flowers yield a thick brown pod of a fruit, contains 2-3 kidney-shaped seeds;
it’s not until rainy season (June through September) that my fatal plant Breeds;
In monsoons, my fruits, capable to produce its best, most toxic beans; indeed;
I am named botanically by appearance of my fruit “a snooping beak-like solid appendage” physo- means “bladder,” at the end of the stigma Beaked;
My toxin is reversible cholinesterase inhibitor, which acts on the autonomic nervous system, leads;
My poison disrupts communication between the nerves and organs of victims, it needs;
In this regard, I acts similarly to nerve gas, which results in contraction of the pupils, recedes;
Profuse salivation, convulsions, seizures, spontaneous urination and defecation, exceeds
Loss of control over the respiratory system, and ultimately death by asphyxiation, as due to secretions, airway blocks & impedes;
Antidote to my poisoning is the slightly less toxic tropane alkaloid atropine, which may often succeeds;
Though myself toxic, my alkaloid proves an effective antidote for poisoning from another deadly plant, Atropa Belladonna seeds;
Guess my name, causing Vomiting, as Lie detector for your means: when an Ordeal poison, impleads;
References:
1. Pillay, VV. Comprehensive Medical Toxicology. 3rd Ed. Jaypee. 2018 p612-15
HIGHLIGHTS OF PRESCRIBING INFORMATION
These highlights do not include all the information needed to us e
M-M-R II safely and effectively. See full prescribing information
for M-M-R II.
M-M-R® II (Measles, Mumps, and Rubella Virus Vaccine Live)
Suspension for subcutaneous injection
Initial U.S. Approv al: 1978
-------------------------------INDICATIONS AND USAGE-------------------------------
M-M-R II is a vaccine indicated for active immunization for the
prevention of measles, mumps, and rubella in individuals 12 months of
age and older. (1)
-------------------------- DOSAGE AND ADMINISTRATION--------------------------
Administer a 0.5-mL dose of M-M-R II subcutaneously. (2.1)
• The first dose is administered at 12 to 15 months of age. (2.1)
• The second dose is administered at 4 to 6 years of age. (2.1)
------------------------DOSAGE FORMS AND STRENGTHS -----------------------
Suspension for injection (0.5-mL dose) supplied as a lyophilized
vaccine to be reconstituted using accompanying sterile diluent. (3)
---------------------------------- CONTRAINDICATIONS ----------------------------------
• Hypersensitivity to any componentof the vaccine. (4.1)
• Immunosuppression. (4.2)
• Moderate or severe febrile illness. (4.3)
• Active untreated tuberculosis. (4.4)
• Pregnancy. (4.5, 8.1)
-------------------------- WARNINGS AND PRECAUTIONS --------------------------
• Use caution when administering M-M-R II to individuals with a
history of febrile seizures. (5.1)
• Use caution when administering M-M-R II to individuals with
anaphylaxis or immediate hypersensitivity following egg ingestion.
(5.2)
• Use caution when administering M-M-R II to individuals with a
history of thrombocytopenia. (5.3)
• Immune Globulins (IG) and other blood products should not be
given concurrently with M-M-R II. (5.4, 7.2)
----------------------------------ADVERSE REACTIONS----------------------------------
See full prescribing information for adverse reactions occurring duri ng
clinical trialsor the post-marketing period. (6)
To report SUSPECTED ADVERSE REACTIONS, contact Merck
Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., at 1-8 7 7 -
888-4231 or VAERS at 1-800-822-7967 or www.vaers.hhs.gov.
-----------------------------------DRUG INTERACTIONS----------------------------------
• Administration of immune globulins and other blood products
concurrently with M-M-R II vaccine may interfere with the
expected immune response. (7.2)
• M-M-R II vaccination may result in a temporary depression of
purified protein derivative (PPD) tuberculin skin sensitivity. (7.3)
-------------------------- USE IN SPECIFIC POPULATIONS--------------------------
• Pregnancy: Do not administer M-M-R II to females who are
pregnant. Pregnancy should be avoided for 1 month following
vaccination with M-M-R II. (4.5, 8.1, 17)
See 17 for PATIENT COUNSELING INFORMATION and FDA
approv ed patient labeling.
Rev ised: 06/2020
FULL PRESCRIBING INFORMATION: CONTENTS
1 INDICATIONS AND USAGE
2 DOSAGE AND ADMINISTRATION
2.1 Dose and Schedule
2.2 Preparation andAdministration
3 DOSAGE FORMS AND STRENGTHS
4 CONTRAINDICATIONS
4.1 Hypersensitivity
4.2 Immunosuppression
4.3 Moderate or Severe Febrile Illness
4.4 Active Untreated Tuberculosis
4.5 Pregnancy
5 WARNINGS AND PRECAUTIONS
5.1 Febrile Seizure
5.2 Hypersensitivity to Eggs
5.3 Thrombocytopenia
5.4 Immune Globulins and Transfusions
6 ADVERSE REACTIONS
7 DRUG INTERACTIONS
7.1 Corticosteroids and Immunosuppressive Drugs
7.2 Immune Globulinsand Transfusions
7.3 Tuberculin Skin Testing
7.4 Use with Other Live Viral Vaccines
8 USE IN SPECIFIC POPULATIONS
8.1 Pregnancy
8.2 Lactation
8.4 Pediatric Use
8.5 Geriatric Use
11 DESCRIPTION
12 CLINICAL PHARMACOLOGY
12.1 Mechanism of Action
12.6 Persistence of Antibody Responses After Vaccination
13 NONCLINICAL TOXICOLOGY
13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility
14 CLINICAL STUDIES
14.1 Clinical Efficacy
14.2 Immunogenicity
15 REFERENCES
16 HOW SUPPLIED/STORAGE AND HANDLING
17 PATIENT COUNSELING INFORMATION
Sections or subsections omitted from the full prescribing info rma tion
are not listed.
2
FULL PRESCRIBING INFORMATION
1 INDICATIONS AND USAGE
M-M-R® II is a vaccine indicated for active immunization for the prevention of measles, mumps, and
rubella in individuals 12 months of age and older.
2 DOSAGE AND ADMINISTRATION
For subcutaneous use only.
2.1 Dose and Schedule
Each 0.5 mL dose is administered subcutaneously.
The first dose is administered at 12 to 15 months of age. A second dose is administered at 4 to 6
years of age.
The second dose may be administered prior to 4 years of age, provided that there is a minimum
interval of one month between the doses of measles, mumps and rubella virus vaccine, live {1-2}.
Children who received an initial dose of measles, mumps and rubella vaccine prior to their first
birthday should receive additional doses of vaccine at 12-15 months of age and at 4-6 years of age to
complete the vaccination series [see Clinical Studies (14.2)].
For post-exposure prophylaxis for measles, administer a dose of M-M-R II vaccine within 72 hours
after exposure.
2.2 Preparation and Administration
Use a sterile syringe free of preservatives, antiseptics, and detergents for each injection and/or
reconstitution of the vaccine because these substances may inactivate the live virus vaccine. To
reconstitute, use only the diluent supplied with the vaccine since it is free of preservatives or other
antiviral substances which might inactivate the vaccine.
Withdraw the entire volume of the supplied diluent from its vial and inject into lyophilized vaccine vial.
Agitate to dissolve completely. Discard if the lyophilized vaccine cannot be dissolved.
Withdraw the entire volume of the reconstituted vaccine and inject subcutaneously into the outer
aspect of the upper arm (deltoid region) or into the higher anterolateral area of the thigh.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to
administration, whenever solution and container permit. Visually inspect the vaccine before and after
reconstitution prior to administration. Before reconstitution, the lyophilized vaccine is a light yellow
compact crystalline plug, when reconstituted, is a clear yellow liquid. Discard if particulate matter or
discoloration are observed in the reconstituted vaccine.
To minimize loss of potency, administer M-M-R II as soon as possible after reconstitution. If not used
immediately, the reconstituted vaccine may be stored between 36°F to 46°F (2°C to 8°C), protected from
light, for up to 8 hours. Discard reconstituted vaccine if it is not used within 8 hours.
3 DOSAGE FORMS AND STRENGTHS
M-M-R II vaccine is a suspension for injection supplied as a single dose vial of lyophilized vaccine to
be reconstituted using the accompanying sterile diluent [see Dosage and Administration (2.2) and How
Supplied/Storage and Handling (16)]. A single dose after reconstitution is 0.5 mL.
4 CONTRAINDICATIONS
4.1 Hypersensitivity
Do not administer M-M-R II vaccine to individuals with a history of hypersensitivity to any component
of the vaccine (including gelatin) {3} or who have experienced a hypersensitivity reaction following
administration of a previous dose of M-M-R II vaccine or any other measles, mumps and rubellacontaining vaccine. Do not administer M-M-R II vaccine to individuals with a history of anaphylaxis to
neomycin [see Description (11)].
4.2 Immunosuppression
Do not administer M-M-R II vaccine to individuals who are immunodeficient or immunosuppressed due
to disease or medical therapy. Measles inclusion body encephalitis {4} (MIBE), pneumonitis {5} and death
as a direct consequence of disseminated measles vaccine virus infection have been reported in
3
immunocompromised individuals inadvertently vaccinated with measles-containing vaccine. In this
population, disseminated mumps and rubella vaccine virus infection have also been reported.
Do not administer M-M-R II to individuals with a family history of congenital or hereditary
immunodeficiency, until the immune competence of the potential vaccine recipient is demonstrated.
4.3 Moderate or Severe Febrile Illness
Do not administer M-M-R II vaccine to individuals with an active febrile illness with fever >101.3F
(>38.5C).
4.4 Active Untreated Tuberculosis
Do not administer M-M-R II vaccine to individuals with active untreated tuberculosis (TB).
4.5 Pregnancy
Do not administer M-M-R II to individuals who are pregnant or who are planning on becoming
pregnant within the next month [see Use in Specific Populations (8.1) and Patient Counseling Information
(17)].
5 WARNINGS AND PRECAUTIONS
5.1 Febrile Seizure
There is a risk of fever and associated febrile seizure in the first 2 weeks following immunization with
M-M-R II vaccine. For children who have experienced a previous febrile seizure (from any cause) and
those with a family history of febrile seizures there is a small increase in risk of febrile seizure following
receipt of M-M-R II vaccine [see Adverse Reactions (6)].
5.2 Hypersensitivity to Eggs
Individuals with a history of anaphylactic, anaphylactoid, or other immediate reactions (e.g., hives,
swelling of the mouth and throat, difficulty breathing, hypotension, or shock) subsequent to egg ingestion
may be at an enhanced risk of immediate-type hypersensitivity reactions after receiving M-M-R II vaccine
.The potential risks and known benefits should be evaluated before considering vaccination in these
individuals.
5.3 Thrombocytopenia
Transient thrombocytopenia has been reported within 4-6 weeks following vaccination with measles,
mumps and rubella vaccine. Carefully evaluate the potential risk and benefit of vaccination in children
with thrombocytopenia or in those who experienced thrombocytopenia after vaccination with a previous
dose of measles, mumps, and rubella vaccine {6-8} [see Adverse Reactions (6)].
5.4 Immune Globulins and Transfusions
Immune Globulins (IG) and other blood products should not be given concurrently with M-M-R II [see
Drug Interactions (7.2)]. These products may contain antibodies that interfere with vaccine virus
replication and decrease the expected immune response.
The ACIP has specific recommendations for intervals between administration of antibody containing
products and live virus vaccines.
6 ADVERSE REACTIONS
The following adverse reactions include those identified during clinical trials or reported during postapproval use of M-M-R II vaccine or its individual components.
Body as a Whole
Panniculitis; atypical measles; fever; syncope; headache; dizziness; malaise; irritability.
Cardiovascular System
Vasculitis.
Digestive System
Pancreatitis; diarrhea; vomiting; parotitis; nausea.
Hematologic and Lymphatic Systems
Thrombocytopenia; purpura; regional lymphadenopathy; leukocytosis.
Immune System
Anaphylaxis, anaphylactoid reactions, angioedema (including peripheral or ****** edema) and
bronchial spasm.
Musculoskeletal System
Arthritis; arthralgia; myalgia.
4
Nervous System
Encephalitis; encephalopathy; measles inclusion body encephalitis (MIBE) subacute sclerosing
panencephalitis (SSPE); Guillain-Barré Syndrome (GBS); acute disseminated encephalomyelitis (ADEM);
transverse myelitis; febrile convulsions; afebrile convulsions or seizures; ataxia; polyneuritis;
polyneuropathy; ocular palsies; paresthesia.
Respiratory System
Pneumonia; pneumonitis; sore throat; cough; rhinitis.
Skin
Stevens-Johnson syndrome; acute hemorrhagic edema of infancy; Henoch-Schönlein purpura;
erythema multiforme; urticaria; rash; measles-like rash; pruritus; injection site reactions (pain, erythema,
swelling and vesiculation).
Special Senses — Ear
Nerve deafness; otitis media.
Special Senses — Eye
Retinitis; optic neuritis; papillitis; conjunctivitis.
Urogenital System
Epididymitis; orchitis.
7 DRUG INTERACTIONS
7.1 Corticosteroids and Immunosuppressive Drugs
M-M-R II vaccine should not be administered to individuals receiving immunosuppressive therapy,
including high dose corticosteroids. Vaccination with M-M-R II vaccine can result in disseminated disease
due to measles vaccine in individuals on immunosuppressive drugs [see Contraindications (4.2)].
7.2 Immune Globulinsand Transfusions
Administration of immune globulins and other blood products concurrently with M-M-R II vaccine may
interfere with the expected immune response {9-11} [see Warnings and Precautions (5.4)]. The ACIP has
specific recommendations for intervals between administration of antibody containing products and live
virus vaccines.
7.3 Tuberculin Skin Testing
It has been reported that live attenuated measles, mumps and rubella virus vaccines given individually
may result in a temporary depression of tuberculin skin sensitivity. Therefore, if a tuberculin skin test with
tuberculin purified protein derivative (PPD) is to be done, it should be administered before, simultaneously
with, or at least 4 to 6 weeks after vaccination with M-M-R II vaccine.
7.4 Use with Other Live Viral Vaccines
M-M-R II vaccine can be administered concurrently with other live viral vaccines. If not given
concurrently, M-M-R II vaccine should be given one month before or one month after administration of
other live viral vaccines to avoid potential for immune interference.
8 USE IN SPECIFIC POPULATIONS
8.1 Pregnancy
Risk Summary
M-M-R II vaccine is contraindicated for use in pregnant women because infection during pregnancy
with the wild-type viruses has been associated with maternal and fetal adverse outcomes.
Increased rates of spontaneous abortion, stillbirth, premature delivery and congenital defects have
been observed following infection with wild-type measles during pregnancy. {12,13} Wild-type mumps
infection during the first trimester of pregnancy may increase the rate of spontaneous abortion.
Infection with wild-type rubella during pregnancy can lead to miscarriage or stillbirth. If rubella infection
occurs during the first trimester of pregnancy, it can result in severe congenital defects, Congenital
Rubella Syndrome (CRS). Congenital rubella syndrome in the infant includes but is not limited to eye
manifestations (cataracts, glaucoma, retinitis), congenital heart defects, hearing loss, microcephaly, and
intellectual disabilities. M-M-R II vaccine contains live attenuated measles, mumps and rubella viruses. It
is not known whether M-M-R II vaccine can cause fetal harm when administered to pregnant woman.
There are no adequate and well-controlled studies of M-M-R II vaccine administration to pregnant
women.
5
All pregnancies have a risk of birth defect, loss or other adverse outcomes. In the US general
population, the estimated background risk of major birth defects and miscarriage in clinically recognized
pregnancies is 2% to 4% and 15% to 20%, respectively.
Available data suggest the rates of major birth defects and miscarriage in women who received
M-M-R II vaccine within 30 days prior to pregnancy or during pregnancy are consistent with estimated
background rates (see Data).
Data
Human Data
A cumulative assessment of post-marketing reports for M-M-R II vaccine from licensure 01 April 1978
through 31 December 2018, identified 796 reports of inadvertent administration of M-M-R II vaccine
occurring 30 days before or at any time during pregnancy with known pregnancy outcomes. Of the
prospectively followed pregnancies for whom the timing of M-M-R II vaccination was known, 425 women
received M-M-R II vaccine during the 30 days prior to conception through the second trimester. The
outcomes for these 425 prospectively followed pregnancies included 16 infants with major birth defects, 4
cases of fetal death and 50 cases of miscarriage. No abnormalities compatible with congenital rubella
syndrome have been identified in patients who received M-M-R II vaccine. Rubella vaccine viruses can
cross the placenta, leading to asymptomatic infection of the fetus. Mumps vaccine virus has also been
shown to infect the placenta {14}, but there is no evidence that it causes congenital malformations or
disease in the fetus or infant .
The CDC established the Vaccine in Pregnancy registry (1971-1989) of women who had received
rubella vaccines within 3 months before or after conception. Data on 1221 inadvertently vaccinated
pregnant women demonstrated no evidence of an increase in fetal abnormalities or cases of Congenital
Rubella Syndrome (CRS) in the enrolled women {15}.
8.2 Lactation
Risk Summary
It is not known whether measles or mumps vaccine virus is secreted in human milk. Studies have
shown that lactatingpostpartum women vaccinated with live attenuated rubella vaccine may secrete the
virus in breast milk and transmit it to breast-fed infants.{16,17} In the breast-fed infants with serological
evidence of rubella virus vaccine strain antibodies, none exhibited severe disease; however, one
exhibited mild clinical illness typical of acquired rubella.{18,19}
The developmental and health benefits of breastfeeding should be considered along with the mother’s
clinical need for M-M-R II, and any potential adverse effects on the breastfed child from M-M-R II or from
the underlying maternal condition. For preventive vaccines, the underlying maternal condition is
susceptibility to disease prevented by the vaccine.
8.4 Pediatric Use
M-M-R II vaccine is not approved for individuals less than 12 months of age. Safety and effectiveness
of measles vaccine in infants below the age of 6 months have not been established [see Clinical Studies
(14)]. Safety and effectiveness of mumps and rubella vaccine in infants less than 12 months of age have
not been established.
8.5 Geriatric Use
Clinical studies of M-M-R II did not include sufficient numbers of seronegative subjects aged 65 and
over to determine whether they respond differently from younger subjects.
11 Description
M-M-R II vaccine is a sterile lyophilized preparation of (1) Measles Virus Vaccine Live, an attenuated
line of measles virus, derived from Enders' attenuated Edmonston strain and propagated in chick embryo
cell culture; (2) Mumps Virus Vaccine Live, the Jeryl Lynn™ (B level) strain of mumps virus propagated in
chick embryo cell culture; and (3) Rubella Virus Vaccine Live, the Wistar RA 27/3 strain of live attenuated
rubella virus propagated in WI-38 human diploid lung fibroblasts. {20,21} The cells, virus pools,
recombinant human serum albumin and fetal bovine serum used in manufacturing are tested and
determined to be free of adventitious agents.
After reconstitution, each 0.5 mL dose contains not less than 3.0 log10 TCID50 (tissue culture infectious
doses) of measles virus; 4.1 log10 TCID50 of mumps virus; and 3.0 log10 TCID50 of rubella virus.
Each dose is calculated to contain sorbitol (14.5 mg), sucrose(1.9 mg), hydrolyzed gelatin (14.5 mg),
recombinant human albumin (≤0.3 mg), fetal bovine serum (<1 ppm), approximately 25 mcg of neomycin
and other buffer and media ingredients. The product contains no preservative.
6
12 CLINICAL PHARMACOLOGY
12.1 Mechanism of Action
M-M-R II vaccination induces antibodies to measles, mumps, and rubella associated with protection
which can be measured by neutralization assays, hemagglutination-inhibition (HI) assays, or enzyme
linked immunosorbent assay (ELISA) tests. Results from efficacy studies or effectivenes s studies that
were previously conducted for the component vaccines of M-M-R II were used to define levels of serum
antibodies that correlated with protection against measles, mumps, and rubella [see Clinical Studies (14)].
12.6 Persistence of Antibody Responses After Vaccination
Neutralizing and ELISA antibodies to measles, mumps, and rubella viruses are still detectable in 95-
100%, 74-91%, and 90-100% of individuals respectively, 11 to 13 years after primary vaccination. {22-28}
13 NONCLINICAL TOXICOLOGY
13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility
M-M-R II vaccine has not been evaluated for carcinogenic or mutagenic potential or impairment of
fertility.
14 CLINICAL STUDIES
14.1 Clinical Efficacy
Efficacy of measles, mumps, and rubella vaccines was established in a series of double-blind
controlled trials. {29-34} These studies also established that seroconversion in response to vaccination
against measles, mumps and rubella paralleled protection. {35-38}
14.2 Immunogenicity
Clinical studies enrolling 284 triple seronegative children, 11 months to 7 years of age, demonstrated
that M-M-R II vaccine is immunogenic. In these studies, a single injection of the vaccine induced measles
HI antibodies in 95%, mumps neutralizing antibodies in 96%, and rubella HI antibodies in 99% of
susceptible individuals.
A study of 6-month-old and 15-month-old infants born to mothers vaccinated with a measles vaccine in
childhood, demonstrated that, following infant and toddler vaccination with Measles Virus Vaccine, Live
(previously US-licensed, manufactured by Merck), 74% of the 6-month-old infants developed detectable
neutralizing antibody titers while 100% of the 15-month-old infants vaccinated with Measles Virus
Vaccine, Live or M-M-R II vaccine developed neutralizing antibodies {39}. When the 6-month-old infants
of immunized mothers were revaccinated at 15 months with M-M-R II vaccine, they developed antibody
titers similar to those of toddlers who were vaccinated previously at 15-months of age.
15 REFERENCES
1. General Recommendations on Immunization, Recommendations of the Advisory Committee on Immunization Practices, MMWR
43(RR-1): 1-38, January 28, 1994.
2. Measles, Mumps, and Rubella — Vaccine Use and Strategies for Elimination of Measles, Rubella, a n d Co n g e nita l Ru b e lla
Syndrome and Control of Mumps: Recommendations of the Advisory Committee on Immunization Practice s (ACIP), M M WR
47(RR-8): May 22, 1998.
3. Kelso, J.M.; Jones, R.T.; Yunginger, J.W.: Anaphylaxis to measles, mumps, and rubella vaccine mediated by IgE to gel atin , J.
Allergy Clin. Immunol. 91: 867-872, 1993.
4. Bitnum, A.; et al: Measles Inclusion Body Encephalitis Caused by the Vaccine Strain of Measles Virus. Cl i n . In fect. Di s. 2 9 :
855-861, 1999.
5. Angel, J.B.; et al: Vaccine Associated Measles Pneumonitis in an Adult with AIDS. Annals of Internal Medicine, 129: 1 0 4 -1 06 ,
1998.
6. Cecinati V, et al. Vaccine administration and the development of immune thrombocyto pe ni c p urp u ra i n ch i ld re n. Hu m an
Vaccines & Immunotherapeutics 9:5, 2013.
7. Mantadakis E, Farmaki E, Buchanan GR. Thrombocytopenic Purpura after Measles-Mumps-Rubella Vaccination: A Systematic
Review of the Literature and Guidance for Management. J Ped 156(4): 2010.
8. Andrews N, Stowe J, Miller E, Svanstrom H, Johansen K, Bonhoeffer J, et al. A collaborative approach to investigating th e ri sk
of thrombocytopenic purpura after measles-mumps-rubella vaccination in England and Denmark. Vaccine. 2012;30:3042‐6.
9. Rubella Prevention: Recommendation of the Immunization Practices Advisory Committee (ACIP), MM WR 3 9 (RR-1 5 ): 1 -1 8 ,
November 23, 1990.
7
10. Peter, G.; et al (eds): Report of the Committee on Infectious Diseases, Twenty-fourth Edition, American Academy of Pediatri cs,
344-357, 1997.
11. Measles Prevention: Recommendations of the Immunization Practices Advisory Committee (ACIP), MMWR 38(S-9): 5-22,
December 29, 1989.
12. Eberhart-Phillips, J.E.; et al: Measles in pregnancy: a descriptive study of 58 cases. Obstetrics and Gynecology, 82(5): 797-801,
November 1993.
13. Jespersen, C.S.; et al: Measles as a cause of fetal defects: A retrospective study of ten measles epidemics in Greenland. Acta
Paediatr Scand. 66: 367-372, May 1977.
14. Yamauchi T, Wilson C, Geme JW Jr. Transmission of live, attenuated mumps virus to the hu m a n p l ace n ta . N En g l J M e d .
1974;290(13):710‐712.
15. Rubella Vaccination during Pregnancy —United States, 1971-1988. JAMA. 1989;261(23):3374–3383.
16. Losonsky, G.A.; Fishaut, J.M.; Strussenber, J.; Ogra, P.L.: Effect of immunization against rubella on lactation products. II.
Maternal-neonatal interactions, J. Infect. Dis. 145: 661-666,1982.
17. Losonsky, G.A.; Fishaut, J.M.; Strussenber, J.; Ogra, P.L.: Effect of immunization against rubella on lactation products. I.
Development and characterization of specific immunologic reactivity in breast milk, J. Infect. Dis. 145: 654-660, 1982.
18. Landes, R.D.; Bass, J.W.; Millunchick, E.W.; Oetgen, W.J.: Neonatal rubella following postpartum maternal i mm un izatio n , J.
Pediatr. 97: 465-467, 1980.
19. Lerman, S.J.: Neonatal rubella following postpartum maternal immunization, J. Pediatr. 98: 668, 1981. (Letter)
20. Plotkin, S.A.; Cornfeld, D.; Ingalls, T.H.: Studiesof immunization with living rubella virus: Trialsin children with a strain culture d
from an aborted fetus, Am. J. Dis. Child. 110: 381-389, 1965.
21. Plotkin, S.A.; Farquhar, J.; Katz, M.; Ingalls, T.H.: A new attenuated rubella virus grown in human fi bro b la sts: Evi d e n ce fo r
reduced nasopharyngeal excretion, Am. J. Epidemiol. 86: 468-477, 1967.
22. Weibel, R.E.; Carlson, A.J.; Villarejos, V.M.; Buynak, E.B.; McLean, A.A.; Hilleman, M.R.: Clinical and Labo ra tory Stu d ie s o f
Combined Live Measles, Mumps, and Rubella Vaccines Using the RA 27/3 Rubella Virus, Proc. So c. Exp . Bi ol. M e d. 1 6 5 :
323-326, 1980.
23. Watson, J.C.; Pearson, J.S.; Erdman, D.D.; et al: An Evaluation of Measles RevaccinationAmong School-Entry Age Ch i ld re n,
31st Interscience Conference on Antimicrobial Agents and Chemotherapy, Abstract #268, 143, 1991.
24. Unpublished data from the files of Merck Research Laboratories.
25. Davidkin, I.; Jokinen, S.; Broman, M. et al.: Persistence of Measles, Mumps, and Rubella Antibodies in a n M M R -Va ccina ted
Cohort: A 20-Year Follow-up, JID 197:950–6, April 2008.
26. LeBaron, W.; Beeler J.; Sullivan, B.; et al.: Persistence of Measles Antibodies After 2 Doses of Measles Vaccine in a
Postelimination Environment, Arch Pediatr Adolesc Med. 161:294-301, March 2007.
27. LeBaron, C.; Forghani, B.; Beck, C. et al.: Persistence of Mumps Antibodies after 2 Doses of Measles-Mumps-Rubella Vaccine,
JID 199:552– 60 , February 2009.
28. LeBaron, W.; Forghani, B.; Matter, L. et al.: Persistence of Rubella Antibodies after 2 Doses of Measles-Mumps-Rubella
Vaccine, JID 200:888–99, September 2009.
29. Hilleman, M.R.; Buynak, E.B.; Weibel, R.E.; et al: Development and Evaluation of the Moraten MeaslesVirusVa cci n e , JAM A
206(3): 587-590, 1968.
30. Weibel, R.E.; Stokes, J.; Buynak, E.B.; et al: Live, Attenuated Mumps Virus Vaccine 3. Clinical and Serologic Aspects in a Fiel d
Evaluation,N. Engl. J. Med. 276: 245-251, 1967.
31. Hilleman, M.R.; Weibel, R.E.; Buynak, E.B.; et al:Live, Attenuated Mumps VirusVaccine 4. ProtectiveEfficacy as Measure d i n
a Field Evaluation, N. Engl. J. Med. 276: 252-258, 1967.
32. Cutts, F.T.; Henderson, R.H.; Clements, C.J.; et al: Principles of measles control, Bull WHO 69(1): 1-7, 1991.
33. Weibel, R.E.; Buynak, E.B.; Stokes, J.; et al: Evaluation Of Live Attenuated Mumps Virus Vaccine, Strain Jeryl Lynn, First
International Conference on VaccinesAgainst Viral and Rickettsial Diseases of Man, World Health Organization, No. 147, M a y
1967.
34. Leibhaber, H.; Ingalls, T.H.; LeBouvier, G.L.; et al: Vaccination With RA 27/3 Rubella Vaccine, Am. J. Dis. Child. 123: 133-1 3 6,
February 1972.
35. Rosen, L.: Hemagglutination and Hemagglutination-Inhibition with Measles Virus, Virology 13: 139-141, January 1961.
36. Brown, G.C.; et al: Fluorescent-Antibody Marker for Vaccine-Induced Rubella Antibodies, Infection and Immunity 2(4): 360-363,
1970.
8
37. Buynak, E.B.; et al: Live Attenuated Mumps Virus Vaccine 1. Vaccine Development, Proceedings of the Society for
Experimental Biology and Medicine, 123: 768-775, 1966.
38. Hilleman M.R., Studies of Live Attenuated Measles Virus Vaccine in Man: II. Appraisal of Efficacy. Amer. J. o f Pu b l ic He a lth ,
52(2):44-56, 1962.
39. Johnson, C.E.; et al: Measles Vaccine Immunogenicity in 6- Versus 15-Month-Old Infants Born to Mothers in the Measles
Vaccine Era, Pediatrics, 93(6): 939-943, 1994.
16 HOW SUPPLIED/STORAGE AND HANDLING
No. 4681 ⎯ M-M-R II vaccine is supplied as follows:
(1) a box of 10 single-dose vials of lyophilized vaccine (package A), NDC 0006-4681-00
(2) a box of 10 vials of diluent (package B)
Exposure to light may inactivate the vaccine viruses.
Before reconstitution, refrigerate the lyophilized vaccine at 36°F to 46°F, (2°C to 8°C).
Store accompanying diluent in the refrigerator with the lyophilized vaccine or separately at room
temperature (68° to 77°F, 20° to 25°C). Do not freeze the diluent.
Administer M-M-R II vaccine as soon as possible after reconstitution. If not administered immediately,
reconstituted vaccine may be stored between 36°F to 46°F (2°C to 8°C), protected from light, for up to 8
hours. Discard reconstituted vaccine if it is not used within 8 hours.
For information regarding the product or questions regarding storage conditions, call 1-800-
MERCK-90 (1-800-637-2590).
17 PATIENT COUNSELING INFORMATION
Advise the patient to read the FDA-approved patient labeling (Patient Package Insert).
Discuss the following with the patient:
• Provide the required vaccine information to the patient, parent, or guardian.
• Inform the patient, parent, or guardian of the benefits and risks associated with vaccination.
• Question the patient, parent, or guardian about reactions to a previous dose of M-M-R II vaccine
or other measles-, mumps-, or rubella-containing vaccines.
• Question females of reproductive potential regarding the possibility of pregnancy. Inform female
patients to avoid pregnancy for 1 month following vaccination [see Contraindications (4.5) and
Use in Specific Populations (8.1)].
• Inform the patient, parent, or guardian that vaccination with M-M-R II may not offer 100%
protection from measles, mumps, and rubella infection.
• Instruct patients, parents, or guardians to report any adverse reactions to their health-care
provider. The U.S. Department of Health and Human Services has established a Vaccine
Adverse Event Reporting System (VAERS) to accept all reports of suspected adverse events
after the administration of any vaccine, including but not limited to the reporting of events required
by the National Childhood Vaccine Injury Act of 1986. For information or a copy of the vaccine
reporting form, call the VAERS toll-free number at 1-800-822-7967, or report online at
https://www.vaers.hhs.gov.
For patent information: www.merck.com/product/patent/home.html
Copyright © 1978-2020 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
All rights reserved.
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A Nov 2017
It came thru on a dagger
Spending my last earn faster
Sped up the toxicology to my master
He leans in with a coarse demeanor
Contemplating courses to make it last her
Devils worship in his eyes are blacker
Souls deepen their bloodied grips harder
Speculation drives the people’s brain madder
Insisting on it’s return to the last crater
We push our own to the edge quicker
Lava molding our faces with anger
Desperately gnawing for clarity's charger
Creating glimpses of light for the masses
Leah R Aug 2016
I drank a lot tonight
I feel trapped
I feel trapped
As trapped as I felt that one time locked in your room for hours

As locked as when you stood between me and the door
Did I say locked? I meant trapped

Is that a cop up ahead?

Remember the night I said "Come outside"?


If I died right now I would be free

And it would be so easy too.

They would find my car and do a toxicology report and find that I had drank but just how much?

Only enough to recognize all of this *******

This is only my first time? I must be a natural
Mateuš Conrad Nov 2017
it feels, given the current commentary
that i not stomping through time
writing history, grunting
the minotaur's hot ooze of breath -
what i think? one word answer -
incompetence -
        like a ******* inheritor of a
fortune, expressing a cul de sac of
said, genetic events...
                there's an aversion to
the original freudian concept of,
castration...
                    there's another,
it lies in the basin of the easily agitate
sphere of divorcing ethnicity
with history...
                              the hot-flush
of unease is ever present...
            there's nothing to think about,
really, in all certainty of the certainty
of thought...
            i am not stomping through
history, at the same time making it...
architect supreme...
         what i feel is that i am walking
on egg-shells,
             ballerina of the shadows -
    i'm not making history,
i am either into being nostalgic about
it, or am tired of studying it...
                    the question of women
is past... provided the allowances
of chess...
               medieval women were more
cut-throat than the men...
              scurrying rats is just an image,
and never an analogy...
             imagery metaphor analogue -
contradictory trinity it would seem...
        but i am still inclined to
retain the image of walking on egg shells
rather than stomping, subsequently crushing
human bones...
               the audacity of the forefathers
does not credit me, nor am i their inheritor...
i am balancing on making history:
without actually making one...
                    the eeriness of impotence
that plagues me is of english birth,
and having perfected this tongue,
marking it with the decisive origins shows
me that i cannot fathom it completely...
only in snapshot...
                           it breeds a trans-ethnic
superstition that is advertised,
                               not exactly undue...
but there this: "castration" discomfort
in speaking english without an accent that
might be distinguishable...
notably: conversations where you are
questioned, and never accepted of
the gravity of an answer being undisputed -
namely the lack of etiquette -
whereby in atomic terms:
party a. resembles ?
  while party b. resembles ! -
                           you can only ask so
many questions before there's no question
left, and the narrative leads into:
                                                      nihil / nothing.
i feel, and that is always more valuable
than i think, that i live in un-historical times,
primarily for the lack of nostalgia...
but at the same time the:
  anaemic actors who have no vitality
and merely spread the weißplage -
the white plague...
                who is to wonder why
there shouldn't be an interest in premature
depression of the young that overshadows
the scarcity of premature dementia,
when premature dementia exposes
the seemingly unreachable strata of vocab?
   to me schizophrenia implies:
inhibition, a repression...
                    the budding flower arising
from decay... a fungus growth on a ****...
but premature depression...
       these kids haven't accomplished anything!
i can understand an old man being
hypochondria-prone and melancholic in
having achieved something!
            i call forth the: weißplage...
the white plague...
                           i ought to be a man
stomping with a minotaur's hoof into
history...
                   instead i am a ballerina "dancing"
through a floor of egg shells,
attempting to not make a pipsqueak akin
to a mouse...
               i'd settle for a rat's gnashing jaw chew...
but no...
                     having acquired this language
i've also acquired its historical ailments...
i've overcome the strata of class-theory,
but i've been unable to overcome
the pathology of using this language -
even if i feel castrated for but a split second,
i am, otherwise, dragged down -
ziehennachunten...
                     it's a white plague -
      a mental virus -
  and i too was one of the people who
believe that a solipsistic membrane actually
existed, and that mental illness didn't
have a contagious element to it,
that mental illness had nothing to do with
virology... how wrong i was...
                    with the abandonment of
respecting asylums, western society
has actually invested in a lunatic contagion...
the spread of islam onto the continent
is merely a compliment of the scythe moon
emblem on a flag...
                 and it happens oh so innocently,
an ex-girlfriend calls you up while
you're on the roof, roofing,
  and she cites: hearing voices...
                    i really wish to find someone
who's interested in the virological nature
of the transmission of mental disorders...
               to finally, ******* bury,
this misconception of a rock-solid-****'s-worth
of argument to idealise on a dualism,
but actually engage with the real problem
within a dichotomy...
                 the mind-body to a mind
is no disparity -
                            the body to a mind is
an automaton rather than a mind-body...
              there is a virology and a toxicology
involved in mental illness...
    you know why charles manson exherted
more influence than all the other serial killers?!
   he played the pawns...
    he was the pontius pilate,
he washed his hands clean,
even though they were bloodied...
       in the end there is a messianic connection,
although on the roman side...
                  whereas others bloodied their
hands, he played a mind game...
             be played with plasticine -
                 which just shows history at its most
animate: with hindsight.
he was but a syringe incision,
   and a tsunami of time...
                  while the others were
   a tsunami barrage of **** -
   and in terms of time: a drop in the ocean...
which will always be barely recognisable or
heard by the waiting echo.
                         that sort of model is
the antithesis of Sisyphus...
  a gentle **** of the stone...
   and just watch the avalanche form...
hardly a mein kampf to speak of...
         he figured out the downhill -
because there was never any uphill
                 to begin with...
          my: a tsunami of time...
                      located in a space
              made by a mere needle incision.
Big Virge Aug 2021
Ya Know The World Is FINE... !!!

It's Humanity's LOSS...  
When We Decide...  
To Behave Like DOGS... ?!?  

The World's WAY BEYOND.............................  ..  
PAYING The Cost... !!!!!  
For Humanity's WRONGS...  
Because The Earth Is STRONG... !!!  
  
And Doesn't Get LICKED...  
Cos' of HITS From The ****... !!!  
Or THONG Based Songs... !?!  
  
The World Says... " GREAT "...  
In The Face of STRAIN... !!!  
  
Cos' Now Human LOSS...  
Is The Planets' GAIN...  
When Human DROSS...  
NO LONGER Stains... !!!  
The Planets' SPACE... !!!!  
  
The Earth I Think...  
Would Tell CERTAIN Man QUICK.
  
"Stop playing you slick !  
You were given a brain for you to think,  
while you engage your brain these days,  
like an ignorant pig whose actions stink,  
of stupid displays, like the weakest link !"  
  
Now I've Said BEFORE...  
It's A... CRAZY WORLD... !!!  
  
But The World's NOT Crazy... !!!  
PEOPLE Are... " Shady "... !!!  
  
ABUSING Our Babies... !?!?!  
Cos' of Mind States... Hazy...  
  
... DRUGGED UP Daily... ?!?...  
Treating Earth Like HADES... !!!  
  
DEMONIC And SICK... !!!  
From Poli-TRICKS To How We Live...  
  
RACISTS.... RAPISTS....
  
People CATCHING CASES...  
For CLEARLY FORSAKING...  
What Some CALL Gods Graces... !!!  
  
In SO MANY Places...  
The Earth SEES WAR... !!!  
  
From IGNORANT Hoards...  
And People Who *****...  
Themselves For WEALTH...  
And THAT... " BIG SCORE "... !!!  
  
So What's In Store... ???  
Is The World Going CRAZY... ?!?  
  
Well I Think The World Maybe... ?  
is Seeing That... Lately...  
  
People THINK CRAZY...  
DEFINES The Word STATELY... ?!?  
  
They're A Bit Confused... ?!?  
When What They CHOOSE...  
Are The Types of ABUSE...  
People SHOULD REFUSE... !!!  
  
Like Treating The Environment...  
As If It NEEDS Retirement... ?!?  
Because of BOMBING TYRANTS... !!!  
Who FEED The Earth With VIOLENCE... !!!  
  
I THINK A Moments..... SILENCE  .....  
Is NEEDED MORE Than SIRENS... !!!  
  
And IGNORANCE Cos' Migrants...  
Are Seen As Being Minors...  
By THOSE Who CLAIM They're MAJOR...  
Because of PRINTED Paper... ?!!!?  
  
That ROBS The World of SAVIOURS... !?!  
  
Like TREES That NEED To BREATHE...................  
To NURTURE And GROW SEEDS...  
Because That's What It NEEDS... !!!!!  
  
NOT Consequential Deeds...  
From Mans' NEUROLOGY...  
Where Acting IRRESPONSIBLY...  
FEEDS The TOXICOLOGY...  
AFFECTING Earths' Ecology...  
  
With What's Known As...  
...... " MYCOLOGY "...... !!!  
  
It's GREEDY Ideologies...  
From EGO-FILLED Autonomies...  
Governed By POOR Policies...  
That Lead Some To Believe...  
  
The Earth is Some COMMODITY...  
To Be Sold To OLIGOPOLIES... !!!?!!!  
  
And THAT THE WORLD...  
And NOT It's Peeps'...  
Has FINALLY Gone CRAZY...  
  
Well WRITTEN In These Lines...  
Are WELL Constructed Rhymes...  
  
That PROVE...  
  
..... " The World IS FINE ! ".....
No matter what stupidness we continue to embrace, I think that, without us, the world will be okay ....
WISEPENNY Jul 2020
POISON FOR PROBLEM
TRICKY NEVER WENT TO SCHOOL HERE
TOXICOLOGY REPORTS
BELLY RULES
WATCHING MEN OF FAME WHITE WASH THE RULES

FOR AN EYE IS INFECTIOUS IN SIGHT
YOU DONT NEED MASKS TO TAKE DOWN THERE KITE

TRIVIAL BUT TRUE DICOP OUT TO BEAR NO MASK IN HAND
OR MAYBE IN ARCANUM STOLEN APON LAND

I TOLD YOU ONCE
I TOLD YOU TWICE
I DONT EAT THOSE PEANUT BUTTERED SPLICED

— The End —