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Chinedu Dike Jan 2020
In a wayward adventure in curiosity —
lured away from savvy of cooler judgment,  
he oversteps the bounds of reality 
into a state of altered awareness.

Overwhelmed by a rapid beginning
of a buzzing sensation — The Rush;
emanating from deep inside him, 
surging along the veins streaming 

euphoria through cells of his entire body:  
inside the body, with warm pleasure waves
flushing over the by now tingling skin
soughing off all unpleasant feelings.

Mouth numbed, limbs heavy, and eyeballs 
rolling back from hitherto an unimaginable
state of bliss, he savours the calm explosions
of the pulsating bubbles in his head.

A magical moment of sheer ******* 
rapture—that ends in a lasting sedation—
during which he's dazed with wonderment
while covered by a cozy blanket of content.

He falls in love with the insidious drug.
And he begins to relish its sweet fruition
in a seemly pattern of use that is put
in the shade to protect his best interests.

A stake in normalcy that seeks to confine
his usage of the opioid to a social occasion.
But soon enough he drifts towards a regular
recreational use; indulging on weekends,

floating, flying, and soaring in wonderful
ripples of pure delight, feeling very mellow
and satisfied, in an illusionary paradise of
forgetfulness where nothing hurts any more.

Bit by bit as time goes by his body builds up
a tolerance for the sedative, prompting his
intake of higher and more frequent doses
to feel as well as to sustain the desired effect.

This occurs because his body attempts to
adapt to the presence of the drug by quickly
breaking it up and purging it out of the system,
thus making it less potent as it was before.

At this stage of his drug abuse he's still able to
control whether to use the stuff or not, where
and when to use it, without stress. He could
also abstain from the opioid fairly responsibly.

But at the limits of his body's flexible response
to the dangerous substance, he begins to suffer
from its unpleasant side-effects that show up
a short period of time following his last use.

The pleasurable, but short-term, therapeutic
effects of the hard drug are now being
overshadowed by several of its undesirable
withdrawal symptoms that manifest as:

fatigue, irritability, cold chills/sweat, itchy skin,
muscle spasms and tremors, body ache, and
stomach cramps among others, with an
increase in his body's cravings for the opioid.

The onset of these torturous side-effects of
the stimulant marks the beginning of his body's
physical dependence on it, as he now relies
on the drug to fend off the terrible affliction.

He has bitten at the bait of pleasure oblivious
of the hook beneath it. The once casual user,
who had thought he could quit the habit at will
without stress, has advanced to problematic use.

The drug has become an integral part of a daily
routine that is gradually heading towards chaos.
Regardless, he's still able to go to work and
take care of his day to day responsibilities.

In time, a new sickness begins to fester inside
him: the opioid is tightening its grip on him,
as his body's physical dependence on it
is now generating his addiction to the drug.

This psychological dependence on the drug
has set in with anxiety disorder accompanied
by emotional and behavioural problems:
the duo classic signs of a progressive disorder.

The drug has become something he needs
to sleep or to fully wake up. His sleeping
pattern has also been altered; up at night
and intermittently dozing off during the day.

As dosage of the narcotic rises, so does
the torture of the painful lows and other
symptoms of addiction, making his cravings
for the sedative increasely more intense.

As it is, he's needs several hits of the drug to
make it through the day. All at once he wants
to use! He begins to look forward to using.
He would ingest the drug in risky situations

such as, while at the wheels of his car or
working at his job; always desperate to avoid
withdrawal symptoms as well as to revel in
the bliss of the drug's comforting warmth.

At times he'd skip work 'chasing the dragon':
pursuing the out-of-reach elation levels of
his initial euphoric high, swinging between
feelings of mediocrity and that of ecstasy.

Always, his body would afterwards crash
below baseline, barely able to cater for his
daily needs. The habit has long ceased
to be the fun that it was intended to be.

Like a vicious cycle the relief from the opioid,
which is not justified by external reality,
is being obtained at the cost of the
worsening addiction and a spike in distress

whenever his body is low on the drug.
The more he indulges on the sedative
to calm his racing mind, the more
its comfort zone seems to be desired.

Disoriented in the rigours of his vice,
he strays in the abyss of drug addiction:
a dark, weary place where priority disorder 
is dictated by events outside of his control.

It is this corrupted impulse control that
causes his sick obsession with the narcotic,
rendering him unfit to articulate rational
thoughts: a chronic brain disorder.

In this harmful shift away from reality,  
utmost in his mind is the insidious drug:
over and above his job, his goals, family,
love, friends, hobbies and personal hygiene.

Oddly enough the foremost essentials of life
like water, food, and sleep are also not spared.
He could be ill and he won't care.
No other thoughts can cohabit in his world.

Emotionally invested in his fantasy world,
the toxic substance has kindled in him
an inner turmoil — setting off an overriding
feeling of emptiness that aches in his heart.

The habit much harder to lose than it was
to find: an ongoing effort to wean himself off
the drug is being crushed by a dysphoric mood
and a sickly feeling that intensify in severity.

These horrifying withdrawal symptoms
are a result of the sedative's induced
alterations in the biochemistry of his
brain's system of reward and punishment.

Instead of a mild, blissful flow of the brain's
happy hormones, as is experienced while
one is indulging in a tasty food, on receiving
a great news, or while engaged in any other

kinds of novelty that fill us with a delicious
pleasure, the opioid whose chemical structure
is similar to that of the natural chemical
messengers of the brain, Happy Hormones,

by mimicking these primary drivers of the
brain's reward system the psychoactive 
drug sends a false signal of euphoria to
the complex *****, triggering an instant

and fast secretion of an abnormally large
amount of the 'feel-good hormones', that
begin to surge along its pleasure pathways
overwhelming the reward centre of the brain.

It is this huge outpouring of happy hormones
in the region that elicites in him a sudden
burst of energy, a pleasant state of mild
drowsiness, mental alertness, relaxation, ...

This already intense, euphoric effect of the
opioid is further amplified by the drug's
blocking of the pain partways of the reward
system, thus dulling his emotions and worries

by eliminating any feeling of sorrow, regret,
guilt, fear, or loneliness. Upon intake of the
mood-altering drug, he would feel warm when
cold, calm when angry, bright when grumpy,

filled when hungry and happy when irritable,
with almost a total refrain from the tendency
to view anything in bad light. This dramatic
result makes every normal thing look better

and brings forth a deep sense of satisfaction
as though all his needs have been met.
However, this almost perfectly desirable 
body and mind experience is an artificial

feeling that only lasts a few hours at most.
When the drug's effects wear off, because
the brain, which has come to rely on the steady
supply of happy hormones, cannot adjust

all at once, it gets stuck in overdrive which
results in the withdrawal symptoms. It is so
because his brain, whose system of reward
and punishment has been tampered with,

seeks to counteract and accomodate for
the sweet thrills of the drug's euphoric high,
by secreting much less happy hormones while
the foodgate of pain hormones is thrown open.

Just like a huge surge of happy hormones
elicits unnatural levels of euphorical pleasure,
a spike in flow of pain hormones produce
in him the torturous withdrawal symptoms.

These unwanted side-effects whose rise and
fall are subject to drug levels in the system,
is the debt he has to pay for the supreme
bliss that is relished during his opioid highs.

It is all about his brain seeking to maintain
Homeostasis: a normal, healthy body function.
Once he's able to amerce with penance due,
he'll feel good again with no need for the drug.

Another flip side of the illicit habit is that over
time, the regular surge in happy hormones
disrupts the resilience of the reward region
of the brain, causing physical changes that

have drastically reduced his brain's ability
to produce the 'pleasure juices', or respond
to any stimulus other than the one being
triggered by the psychoactive substance.

This is clearly seen in his lost of interest in
activities that he once enjoyed, since his brain
suffers from lack of happy hormones which
influence one's capacity to be in a good mood.

Because the narcotic has also disrupted
activities in the control region of the brain,
his whole thought pattern, perspective and
behaviour, all radically change along with it.

It is this reprogramming of his brain that has
altered the interior reality of his mind, in ways
that result in him going into 'survival mode'
in the absence of the drug during a withdrawal.

While in this irritable, aggressive and erratic
state, he would forego anything and everything
to obtain the narcotic because he's thinking
of his drug use the same way an individual 

who is parched with thirst thinks of water.
This desperation in seeking out the drug as
a vital lifeline is due to his compromised brain
'thinking' it needs it as a matter of survival.

A habit he had maintained at the outset
because it made him feel extremely good
has tuned against him, quite often, coercing
him to use for the avoidance of pain.

The sedative as dear and painful to him
as an imbecilic child is to its mother,  
he continues on the foreboding route 
for which he has no power of deviation.

Despairing in the clutches of addiction,
the drugs traumatize him, they infuse
toxins into his spine, and he wouldn't
know whether he's coming or going.

He's kept on saying to himself, 'I'm going
to quit for good after using one last time.'
But that remains to be seen as the drug
goes on dulling his inner light day by day.

In a downward spiral that stuns those 
acquainted with him, he loses his job,
his car is repoed, and he's evicted from
a nice home that had been stripped bare.

Drowning in unpaid bills and desperately
in debt having blown an entire life-savings
on the drug, the loss of everything and a few
remaining friends leaves him fatally devastated.

The dangerous drug has evoked a negative
ripple that is felt throughout all that he's
part of. An awful realization that settles in
with cold clarity, eliciting a lurch of dismay

over his dire ignorance about the drug
which has led to the ugly entrapment.
In deep, sorrowful thoughts consumed
with self-loathing he puts a curse upon

the day he first laid eyes on the hard drug.
With the best resolve he's able to muster,
driven by exasperation to kick the habit,
he strives to make his will like stone —

a facade that is soon razed by his urgent need
for the ****** to stave off withdrawal. With a
burden of guilt and shame that can't be faced
he retreats into the haze of his own misery.

With more problems and stresses than ever
he plunges from troubled life to no life,
completely losing touch with reality as the
disorder assumes a more dangerous form.

His fixation on the ****** has taken a turn for
the worst. Besides his strong cravings for it
to ward off withdrawal as well as to experience
its euphoric high again, it has become more

crucial than ever for him to keep his emotions
constantly desensitised to life, by numbing
the agony of living to ease the passage of
day with purchased relief from the sedative.

Locked in this highly destructive pattern
of drug use, he would stop at nothing
to feed the habit: he would cheat, steal,
lie or betray no matter who to get his 'fix'.

Like the spreading of cancer in the body,  
his affliction has metastasized way 
beyond him, chipping away at the sense
of wellbeing of everyone around him.

As frequent and ready targets for theft
his family have to always watch out for him,
in a resentful relations in which they never
could feel at easy with him around their home.

Wallets, jewellery, gadgets, or any other
easy to carry household valuables, that are
not safely locked away, will go missing.
For days at a time he, too, will vanish.

He'd eventually return like the 'prodigal son'.
Always, he's found the door open after
prolonged periods of avoiding home, even
on occasions when he'd been kicked out.

In the many months gone since losing his
source of livelihood, he's been pushed
into a number of rehabilitation facilities,
but as yet has failed to clean up his act.

He's also been in and out of rehab thrice
following hospital discharges for drug
overdose. On the last occasion, he was
found passed out in the family's bathtub.

Timely arrival of the paramedics had saved
his life. Notwithstanding, a nagging urge
to 'use' continues to feed and reinforce
the habit after each discharge from rehab.

It's been most upsetting to the parents
who have had to watch him visibly change
before their eyes: from a good, healthy
son, who had always had his act together,

to as it is, a thin, patchy-skinned loner with
a baffled demeanour — who buries his head
in low self-esteem to conceal the frequent
dilated and glassy pupils from mutual gaze.

Nothing points more to the helplessness 
of the family's plight than having to finally
admit to their little, or no influence, over
the ravages of the stigmatized disorder.

A harrowing experience for a household
whose life-savings, along with compassion
for him, have completely been exhausted
with no more tears remaining to shed.

The hurting family at the end of its tether
confronts him with an ultimatum:
to get his life in order or face the music.
Coldly, they all watch him leave home.

His descent into the final stages of rock-
bottom has been swift. He starts by crashing
on fellow addicts' couches and floors,
but soon his welcome quickly wears out.

Now among the ranks of the homeless the
hobo would wake up feeling sick, and his day
would consist of shoplifting, petty thefts,
begging, and struggling to find others ways

to obtain money in order to feed the habit.
At nights, even on stormy ones, the rough
sleeper would crash wherever there's shelter,
never worrying about waking up the next day.

A hellish existence on the street that has
provoked a string of run-ins with the law. 
Nabbed stealing on ill-fated occasions,
he's manhandled in a most indecent way.

Tired, hungry and sick, the erstwhile ray of
hope, who once had a strong sense of self,
is currently a nervous wreck who envisages
life through the lens of opioid stupor.

Much beyond his ability to ask for help, 
his hurting family proceed to rescue him.
Under the humbling load of drug addiction
he staggers into another rehab facility.

But the often slippery climb to recovery
is never easy. It's yet another chance for him
to submit to a slow and delicate therapy on
his brain, whose structure and functions are

badly impacted by years-long use of the drug.
The healing process is a labour of discipline
and commitment, coupled with patience
in order to allow the brain to adapt back

toward normalcy by gradually regenerating
and rebalancing itself. In a gruelling task he's
expected to learn to care for a body that
now must struggle to work in a different way.

Desiring to put their lives back together many
druggies have been able to crawl their way out
of the murky shadow — a big chunk of them
through the guiding light of structured help.

Amongst them were 'walking corpses' whom
possessed by their 'enough is enough', were
enabled to find the inner fire vitally needed
to rekindle the cold embers of self-image.

There's the fella cast adrift feeling wholly
disconnected from self and the world.
He's mourning the loss of a vital lifeline
that has always helped him cope with life.

He had been through it many times before,
the fatigue, stomach cramps, aches, itchy skin, ...
But, he's in the early stages of withdrawal when
cravings for the narcotic are at their worst.

This initial withdrawal agony is the biggest
hurdle any addict has to overcome in the often
stop-start journey to recovery. If he could
somehow find the courage to suffer through it,

the fierce and ceaseless cravings for the drug
would be considerably reduced, making
them easier for him to deal with. Eventually,
they will dissipate the longer he stays sober.

He's being offered a way out of his captivity,
but he's unable to embrace the opportunity
with open arms because the addiction,
which convinces him the only option available

is to indulge on the drug, is blocking him from
seeing the available escape route. It has shut
off his ability to get up on the inside to face
the seeming overwhelming barriers to sobriety.

Like one in the grip of Stockholm Syndrome,
he has developed a type of trauma bonding
with the treacherous drug: the more it hurts
him, the more his irrational affection for it.

With his consciousness constantly revolving
around the insidious substance, he just
can't imagine a chronic user like him
being sober and happy again without it.

That being the case, he fails to see any point
in struggling to remain sober when in such
times he's beset by an awful illness attended
by a serious depression that is no help.

Regardless of the wreckage of his past,
everything that is dear to him plus the very
essence of life on the line, he's left convinced
that giving up the destructive habit would

mean endless suffering and feeling deprived
for the rest of his already sad existence.
More than any other reasons, he just
won't quit because he's powerless to resist.

In default of any dreams of ever recouping
losses that are manifestly out of reach,
the drug with a firm grip on him serves 
as a buffer to keep his ugly reality at bay.

All that he wants is to return to the 'loving
arms' of the opioid, very much aware that
the feeling of the drug's high now that he's
in pain can be one of the best things ever.

But even so, as tempting as the desire to jump
the healing process may be, he's bitterly
mindful of the horrors of street life that
loom upon him with such frightening aspect.

Savagely trapped with no good choices he
slips into a real fear of relapse. In anguish
withdrawal and cravings plague him daily,
and they won't allow him a moment's peace.

Utterly incapable of rising from the ashes 
to hold it all together—no hope—
nothing to hope for—everything out 
of focus—mind spiraling out of control.

In a fit of extreme anxiety the now rampaging
urge to 'use' prods him, closer and closer,
to the brink of a nervous breakdown. Suddenly,
his need for a 'hit' becomes most vital as.

Sweating profusely and trembling all over
with fear clutching a pilfered smartphone,
forgetful of future suffering the rehab
jumper hurries along the forbidden path.

All alone with the merciless companion: 
nowhere to go and no one to turn to. 
Wretchedly wretched in additive agony
the ****** fades away into nothingness.








AUTHOR'S NOTE


The Abyss Of Drug Addiction is written in 112 non-rhyming quatrains.

The rendition is a poignant story depicting the sad existence of many drug users. The verse uncovers and illuminates, step by step, the different stages of drug addiction and the mental processes of the unable to function drug users.

The paramount aim of the work is to shed some light on the sinister shadow of drug addiction: to unveil to all and sundry, especially teenagers and the youths, the hazards of drug abuse and the vicious downward spiral that can be caused by it. 

Just as the euphoric experience of all kinds of hard drugs differ significantly, so are their withdrawal symptoms. Despite their seeming surface unrelatedness, whichever hard drug it may be, the creation of an illegal and dangerous dependency in users is a common denominator.

[The Rush is described as a feeling very much like a heightened and prolonged ****** ******. A great relieve of tension. It is mostly felt when ****** or any of it's derivatives opioids/opiates is administered intravenously].

In quite a disturbing hyperbole a ****** addict described the drug's EUPHORIC RUSH as follows:
"Take the best (******) ****** you've ever had, multipy it a billion and you're still no where near it... "
I thought it right to assess some antidepressants, which philosophers are more inclined to call mood enhancers.
This was during my foray into human enhancement, substances intended to enhance physicality, cognition or mood. Nootropic compounds concern the latter two categories.

The most commonly prescribed mood enhancers are serotonin reuptake inhibitors (SRIs), but it takes over a week for these compounds reach their peak effect.
Thus I approached them with the notion that a limited dosage might point to their character, though  not reveal. These considerations in mind, I set about acquiring a few miscellaneous anti-D's.

Fluoxetine was the first successful selective serotonin re-uptake inhibitor (SSRI), better known by its original brand-name Prozac. Fluoxetine has an acute biological half-life of between 1-3 days. Presence of a trifluoromethyl group on the compound deserves note, I wonder what the presence of electronegative fluorine atoms add to the psychoactive flavor of a compound (subjective effects).
I administered a single dose by mouth, there was some indication of subjective character. Light serotonergic sensations and seemingly benign mood-dampening, there is a ****** towards the positive. Waking headspace relatively uninteresting. Observed hints of oneirogenesis, did not manifest in enough character to be detailed - a sort of vivid, 'pulsive wandering, more pronounced in contrast to its waking character.
Good experiment, interesting results.
Ligand     Ki (nM)   Ki (nM)
Target      Flx            Nflx
SERT        1               19
NET         660           2700
DAT         4180         420
5-HT2A   200           300
5-HT2B    5000         5100
5-HT2C    72.6          91.2
α1             3000         3900
M1            870           1200
M2            2700         4600
M3            1000         760
M4            2900         2600
M5            2700         2200
H1            3250         10000

Sertraline is another popular SSRI, also known by it's original brand-name Zoloft. Sertraline has a variable half-life, on average 26 hours.
It's metabolite, desmethylsertraline, has a half life between 62-104 hours but is a far less potent Serotonin Releasing Agent (SRA).
The presence of two chlorine atoms is interesting. The usual, phenomenal serotonergicity is present and pushing towards the positive.
Some nausea, particularly when hungry (this disappeared after some minestrone soup). Some faintness after physical exertion. This dose did not promote onirogenesis. There was a moment of cognitive distortion when the proportions of a focal object seemed to be growing in-and-out, shifting in size.
Site                 Ki (nM)
SERT              0.15–3.3
NET               420–925
DAT               22–315
5-HT1A       >35,000
5-HT2A          2,207
5-HT2C          2,298
α1A        ­        1900
α1B                 3,500
α1D                 2,500
α2                  477–4,100
D2                  10,700
H1                  24,000
mACh           427–2,100
σ1                   32–57
σ2                   5,297

Escitalopram is an SSRI commonly prescribed for major depression and generalised anxiety. It is the (S)-stereoisomer of citalopram. The biological half-life is of escitalopram is between 27-32 hours.
I administered a dose and thought the phenomenal serotonergicity less apparent than fluoxetine but then gastro-intestinal disturbance was noted, I surmised it has a high affinity for 5-HT2C.
Any oneiric qualities were not readily apparent after a single dose, relatively little visual imagery which is understandable given its lack of affinity for 5-HT2A. I found this to be philosophically interesting. Mood elevation observed in bursts of conversation and as odd sensations, possible mental discomfort.
Ligand,
Recptr     Ki (nM)
SERT       2.5
NET        6,514
5-HT2C   2,531
α1            3,870
M1           1,242
H1           1,973

Venlafaxine is a selective serotonin-norepinephrine reuptake inhibitor (SNRI). Venlafaxine and its metabolites are active for about 11 hours.
Initial subjective effects similar to a very light empathogenic stimulant. Perception of altered attention-span/increased reflexive response; energizing yet paradoxically much yawning.
Ligand,  Vnfx      Dvnfx
Recptr    Ki(nM)  Ki(nM)
SERT  ­    82           40.2
NET       2480        558.4

Tianeptine is a tricyclic antidepressant (TCA) with an unusual mechanism of action. It is an atypical agonist of the μ-opioid receptor and has been described as a (selective) serotonin reuptake enhancer (SRE). It has a short duration as sodium salts [prescribed form] of between 2-4 hours but as sulfate this can be notably extended, some of its metabolites are active for longer than tianeptine itself.
Definitely anxiolytic, quite artificial; possible aphrodisiac. I find its opioid activity dissuading, requires caution.
Site          Ki (nM)
MOR       383–768 (Ki)
                 194 (EC50)
DOR      >10,000 (Ki)
                 37,400 (EC50)
KOR      >10,000 (Ki)
                 100,000 (EC50)
All other transporter/receptor/sub-receptor values are >10,000 (Ki).

Bupropion is a norepinephrine-dopamine reuptake inhibitor (NDRI) with affinity for some nicotinic receptors. Bupropion and its metabolites are active for between 12-36 hours. Interestingly it is a substituted cathinone.
Initial subjective effects similar to a fairly light stimulant. Perception of increased attention-span and improved cognition. It is an onirogen that is neutral in quality, enhancing vivid dreaming (a boon of its nicotinic affinity which is counteracted if the stimulant component impinges on sleep). Completely absent of serotonergicity, curious.
The N-tert-butyl group's effect is most interesting, how it affects metabolism and to what extent ROAs alter pharmacokinetics.
I took 150mg ******, as extended and as instant release (the latter was more pronounced). I thought an altered pharmakinetic profile might result from bypass of hepatic metabolism, so I tried 25mg insufflated and felt as if there was effect that it differed slightly from oral ROAs, but also worried that its metabolic fate is thence unknown (compare to the neurotoxic 3-CMC). What of other bupropiologues,
for example, 3-Methyl-N-tert-butyl-methcathinone? Indeed.
                        Bupropion    R,R-Hydroxybuprpn   Threo-hydrobuprpn
AUC               1                     23.8                                  11.2
Half-life         11 h                 19 h                                 31 h
IC50 (μM)
DAT               0.66                  inactive                          47 (rat)
NET               1.85                   9.9                                  16 (rat)
SERT              inactive          inactive               ­            67 (rat)
α3β4 nic         1.8                   6.5                                   14 (rat)
α4β2 nic         12                     31                                   no data
α1β1γδ nic     7.9                    7.6                                  no data

Moclobemide is a reversible inhibitor of monoamine oxidase A (RIMA), its monoamine oxidase inhibition lasts about 8–10 hours and wears off completely by 24 hours. Inhibiting the decomposition of monoamines (e.g. serotonin, norepinephrine and dopamine) increases their accumulation at an extracellular level. It tends to suppress REM sleep and so it lacks oneirogenic properties.
Feeling of well-being, less constrained by the usual anxieties; openness. Relatively unnoticeable side-effects when diet is carefully managed. Made the mistake of eating a cheese and turkey sandwich (i.e. foodstuff rich in tryptophan/tyramine), indications of serotonergicity later became apparent: feelings of overheating and flushing, slight sweating, racing thoughts and anxious discomfort. A stark reminder of Shulgin's old adage: "there is no casual experiment".
Combination with a select few tryptamines (not 5-MeO-xxT) should be safe, and synergistic (perfect for pharmahuasca); reputed to potentiate GHB. However, generally it is extremely dangerous to combine with serotonergic drugs.
Àŧùl Jan 2016
Licking the ***** off the small peaks,
Each dilated eye in ecstasy truly speaks.

The peaks are so natural button-like soft,
Conveying sans the speech the desire oft.

Whenever stiff & excited about to burst,
Titillating the sensuality be with trust.
My HP Poem #991
©Atul Kaushal
All observation is from a particular point, but
acknowledged subjectivity's better than naught.
Thus follows some comments on their qualitative nature.
Use them as you deem. In this piece everything is as it seems.

Caffeine is unappreciated enough,
Give credit to that stimulant for the things it does.
Coffee has little time to play, for there are errands
to attend to before the light fades.

The amphetamine will spin you until you're spun,
The cathinone will also try you with its luck.
The stimulant is a trickster [touch within]
and a magician never reveals their secret,
Even when seeking it befalls endlessness.

Me and E(cstasy) used to dance all night,
Closer to all your dreams was as far
from the light, we soaked ourselves
in emotionality and I soared high:
Perfection in the dark
rekindled my heart
; 'cause
on pills you love everyone.

******* is always hungry but will never feed you
for it is naught but the scent of pure ego;
because on coke everyone loves you.

There is nothing to learn from an opioid or benzodiazepine
beyond the hedonistic stupor in-between awake and sleeping.
Similarly, cigarettes never taught me anything about myself
much like quick, ***** ***, that's nicotine and painkillers, in essence.

Alcohol is reliable for those sociable
but can hurt the body and scorn the emotional.
Drink toyed with me, then she abandoned me;
Despite that messiness I still reminisce occasionally.

Gamma-HydroxyButyric acid [GHB] requires utmost caution,
One must observe the proper conduct when
wading through such subtle intoxication.

Don't use ket too much, don't use angel dust.
If you want a supreme arylcyclohexylamine
seek out methoxetamine, use it responsibly.
Dissociation, end of line; no[thing is o]ne.

Always be considerate before transcending reality,
Reverence for psychedelics keeps them self-regulatory.
Of all the compounds they would humble and reveal to you;
Existential, being when tripping; every[is]one.

Cannabis I dared to use recreationally
for it often reminded us when one should act sensibly.
That deep conversing with trusted friends
is better than any substance I have ever had the nerve to test
.
I was seeking to be lost,
In that journey I found myself
and composed this journal from said
fearfulpoet Aug 2018
surrender and defeat,
my fated causality,
by mine own hand done in,
'twas the death I ordained,
when to the addiction of ego,
I did, did I,
concede and become another casualty
by mine own mind
Xyns  Jun 2018
Rusty
Xyns Jun 2018
Eyes wide shut in a poppy seed slump
Slow motion moves my blood as it pumps
Cold and coping with pale powder bumps
I find my crutch in a poppy seed slump

Dumb and numb, opioid ****
Laying limp in a rut


*** on the run, opioid rust
Praying lips of a mut


Dumb and numb, opioid rust

Cheap opioid ****
James Floss Apr 2017
I am reading poems by Billy Collins:
AIMLESS LOVE, a retrospective,
A sampler, as it were
For the Books and Brew;
Our monthly selection.

Nine manly men
Meeting for monthly meals
And book-talk
And politics
And, of course, good beer.

They like nonfiction,
I like fiction.

Richard Hughes,
British writer of poems, short stories, novels and plays said:
“All nonfiction can do is answer questions;
It is fiction's business to ask them.”

Still, my repertoire has expanded:
Nike shoes.
Civil War.
Institutional racism.
Opioid addiction.
Rafting the Grand Canyon.
Climbing mountains.
With Baron Von Humboldt.

And now this:
Poetry.
Nine manly men
Reading poetry to each other
While sharing a meal,
One lovely poem after another.

You can't read a book of poetry
Like you consume other books,
Fiction or nonfiction.

The table of contents:
The lid of a box of exquisite truffles—
A map of pleasures contained within.
You look at the map,
And make a selection.

The caramel truffle
Is not the coffee truffle.

You look at the map,
Make a selection,
And bite!

The crusty chocolate cracks!
The darkness melts,
Floods your mouth with taste.

Then the rush of caramel!
Flavors, smells sloshing
Swooning with sensate memories.

What? Turn the page and read another?
Reach for the coffee truffle?

No. Linger with caramel;
Luxuriate on aftertaste.
Is that a note of citrus or salt?

I will enjoy my coffee truffle tomorrow.
one who basks in the soft heat of grandiose moonliness
growing fatter on honeyed imaginations
their sicklysweetness soaking through the pores
of countless generations
their minds invade a collective consciousness
burning arcs of inspiration – torches of the collective vision
in drilling through mutual experience
great gaping black holes of creation
effigies of super-egos, lynched on altars of desire
neon flames and disco lights, emotions on a massive pyre
maiden voyagers on never-ending cruise
sinking in foreign oceans – their endurance dupes
minor gods of destiny and fate they await
dionysian ****** of wine and food for thought
and hearts that beat in unison
a schizoid muttering that enlarges and deafens
manic pleasure that spins and spins
in eternal circles of pleasure and pain, loss  and gain
opioid mists that dream a dream of everlasting name
an addiction an obsession that sumbits
to some masochistic drive
to empathize.

- Vijayalakshmi Harish
        06.09.2012

Copyright © Vijayalakshmi Harish
”The courage of the poet is to keep ajar the door that leads into madness.” - Christopher Morley
Cedric McClester Apr 2017
By: Cedric McClester

I’m hurt and I’m confused
Got a bad case of the blues
Opioid addiction’s old news
'Cos someone lit the fuse
And now you find it everywhere
In places where they didn’t care
But life indeed can be unfair
So they’ve become aware

Just say no was like denying
That whole communities were dying
Then we discovered they were lying
Iran Contra revealed them buying
Drugs that kept our communities addicted
Not in the least were they conflicted
‘Long as they thought it was restricted
To the areas that they conscripted

Because it has become systemic
Now it’s called an epidemic
And treatment is the new polemic
The rest I guess is academic
And so I wonder where to begin
Treatment was the thing back then
Until prevention made its way in
Now maintenance happens to be back again

Medical professionals now treat the affliction
That politely is known as opioid addiction
If they didn’t it would be dereliction
Of office treatment in their jurisdiction
Some of you may not be aware
That opioid addicts can get office care
For many of ‘em it’s an answer to a prayer
A stigma free environment beyond compare









Cedric McClester, Copyright © 2017.  All rights reserved.
Hooflip  Feb 2014
Opioid
Hooflip Feb 2014
With every step
I stay
the exact,
Perfect
distance,
from a bonfires heat.
https://soundcloud.com/thehumbleloud
David Barr Jan 2014
I have an insatiable appetite for oxymorons, as they can be violent in their state of calm relaxation.
Although Bacillus anthracis is truly antisocial within the context of biological weaponry; so, domestic discipline has become intertwined with the Hindu philosophy of Vatsyayana.
So, what do you think about that?
Personally, I have never consumed methylated spirits even though I have unravelled a myriad of ideologies whilst my boots concealed precious opioid syringes.
Therefore, always reflect upon the Code of Hammurabi, because she is the epitome of savory stew.
How alternative are your affiliations?
Cedric McClester Nov 2017
By: Cedric McClester, Copyright (c) 2017

Am I dating myself
With these words out my mouth?
See, I remember a time
When we flashed the peace sign
And called one another
Sister and brother
Seems we’ve gone sour
On acquiring black power
And black on black crime
Is the new paradigm
When we look in the mirror
It becomes much more clearer
That we hate what we see
Although that shouldn’t be
Remember freedom marches
Before the golden arches

Then ****** entered in
And we start popin’ our skin
Before we shot it straight into our veins
Which probably explains
Why we regressed
Long before the present opioid mess
It was ****** first,
But then it got worst
So let me take you back
To the era of crack
When a nickel or dime
Could trigger a crime
And what really hurt you
Is the women who lost their virtue
But I’m not absolving the men
Who’d engage in all kinds of sin

I remember gangster rap
And how that set the trap
Which brought the stress and strife
From tryna live that gangster life
Then the East Coast West Coast war
That didn’t exist before
Remember when Biggie and Tupac were friends?
Instead of how their story ends
They’ire a classic group today
But I remember when NWA
Used to pull out all stops
When they sang **** the cops
And chronicled their lives
Called their girlfriends and their wives
All kinds of ******* and ******
Then would dance down on all fours

Now let me bring you up to date
Would it be wrong for me to state?
When it was our problem alone
It was the prisons we were shown
There was little sympathy don’t cha see
When it  was just you and me
Who said they had a problem
There were few out there to solve ‘em
But opioids are everywhere
And it’s a disease now, so I hear
That crosses all socio-economic lines
Now there are many telltale signs
It’s now called an opioid disorder
Past the inner city border
And the word is harm reduction
Instead of out and out destruction






















Cedric McClester, Copyright © 2017.  All rights reserved.
r Jun 2014
Peering through a wasp's wing
at shadows on the wall
Hear the whispered whimper
echo down the hall
Glass thump of bone and feathers
against the bedroom window
Motes of darkness floating
to air a moldy winnow
Creak of standing knees
rise in opioid haze
To wander past the shadows
and sniff of death's bouquets.

r ~ 6/11/14
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