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John F McCullagh Aug 2014
When Ebola’s fever begins to rage,
The prognosis isn’t nice,
Monoclonal antibodies
are needed from three mice.
The mice must first become exposed
to a weakened viral strain.
Their antibodies harvested
and combined with those of man.
Strangely the proteins that we need
are grown best in a ****.
A modified tobacco plant
will do the job indeed.
The serum, that derives from plants,
had not had human trials.
(but eight of ten young chimpanzees
endorse  what’s in that vial.)
Our missionaries, sick unto death
were clearly in no position
to refuse to try the medicine
that might provide remission.
Their rebound was miraculous.
To Atlanta now they fly.
Man finds himself in debt to a mouse.
“Good job, little guy!”
Mapp is a biotech company that produces the serum that has apparently saved two American missionaries from the Ebola virus. Their approach involves recombinant DNA to harvest antibodies from mice exposed to fragments of a dead ebola virus. Tobacco plants are used as a host to grow the monoclonal antibodies in volume to produce the serum
Ryan O'Leary Dec 2024
POEMS syndrome is a rare blood disorder that can affect multiple body systems, including the nerves, organs, and skin. The name POEMS stands for the syndrome's most common signs and symptoms:
Polyneuropathy: Nerve damage that can cause pain, tingling, numbness, or weakness in the legs and hands, and difficulty breathing
Organomegaly: Enlarged liver, spleen, or lymph nodes
Endocrinopathy/edema: Abnormal hormone levels that can lead to diabetes, hypothyroidism, ****** problems, fatigue, and swelling in the limbs
Monoclonal protein: An abnormal protein produced by abnormal plasma cells in the bone marrow
Skin changes: Darkening, thickening, red spots, or increased ****** or leg hair
What Is POEMS Syndrome? An Overview
POEMS syndrome is caused by abnormal plasma cell function in the bone marrow. The abnormal plasma cells release a monoclonal protein into the blood, which can damage nerves and organs.
An early sign of POEMS syndrome is papilledema, which is reported in 29–64% of patients. Papilledema correlates with poor prognosis.
Nerve pain is common in POEMS syndrome and can be treated with drugs such as amitriptyline, gabapentin, or pregabalin.



Ps.

According to my doctor
I am suffering from a rare
form of compulsory poetry
disorder with my current
count of 5,733 poems and the
Guinness book of records
holder John Bradburne had
6,000 composed at the time
of his death. As he is not there
to continue the challenge, I
will not take his record away
from him, but I will be exceeding
six thousand poems early 2025.

— The End —