Brain images Registration Cost Function Weighting Cover unhealthy tissue Clinical settings rating Don't base, registration calculations, in that space Algorithm you will be told, what parts of the brain to scan Be bold Non- Linear transformations, Changes the shape Groups How much has changed, in the clinical range No Linear defamation Tools Adjust Grid squares that operate, independently is a must FAST image pre-lined Initial step Brighter or darker Different sensitivity received Histogram Tissue intensity distributions, exact intensity values span Estimate Bias fields correction Original Bias No restored images aboard Intensity variations across segmentation Applaud Update Segmentation and tissue class Look at my neighbours Mean and standard deviation, group relation Volume model station Spatial neighbouring information Statistics relation, add to the information Partial volume modelling GM Grey Matter and CSF Improving volume estimation Yes Location Configurations from the intensity Spatial neighbourhood what can we see Balance Neighbours or intensity