Disease Arthritis Drug Doubled Risk of Serious Heart Problems, Heart Attacks
By Jeanie Lerche Davis FROM THE WEBMD ARCHIVES Jan. 24, 2005 --The arthritis drug Vioxx may have caused up to 140,000 cases of serious heart disease, including many deaths, new research shows.
The study provides more evidence on the risks of Vioxx, the arthritis drug removed from the market last year. The report appears in this week's issue of The Lancet.
Last year, a study showed that patients taking higher doses of Vioxx (more than 25 milligrams daily) had triple the risk of heart problems, including heart attacks and sudden deaths. The drug was voluntarily pulled from the market in September 2004.
Vioxx Settlement In November 2007, drug maker Merck & Co. announced it would pay $4.85 billion to resolve claims that its anti-inflammatory medication Vioxx caused heart attacks and strokes (including sudden cardiac death). The Vioxx settlement remains the largest pharmaceutical settlement in history.