I've been acquainted with the following
psychoactives compounds:

Depressants & Dissociatives;
Ethanol / EtOH / alcohol, drink, *****
γ-Hydroxybutyric acid / GHB / G, fantasy
β-Phenyl-γ-aminobutyric acid / PhGABA / Phenibut
Dextromethorphan / DXM / Benylin, Robitussin
Morphine / Papaver somniferum / *****
3-Methylmorphine / Codeine
Dihydrocodeine / DHC
Buprenorphine / Subutex, Suboxone
N-Allylnoroxymorphone / Naloxone / Suboxone, Narcan
Tramadol / Ultram
O-Desmethyltramadol/ O-DSMT / Omnitram
Thiopental / Sodium Pentothal
Diazepam / ******
2'-Chlorodiazepam / Ro5-3448 / Diclazepam
4'-Chlorodiazepam / Ro5-4864
Chlordiazepoxide / Librium
Gidazepam, hidazepam
Desalkylgidazepam / Bromonordiazepam
N-Desalkylfluarazepam / Norfluarazepam
Flubromazepam
Alprazolam / Xanax
Bromazolam / XLI-268
Clonazolam, Clonitrazolam / Clam
Etizolam / Etilaam, Etizest
Flualprazolam
Flubromazolam
Zopiclone / Zimovane
Pagoclone
Promethazine / Phenergan
Diphenhydramine / DPH / Benadryl, Nytol
Chlorphenamine, chlorpheniramine / CPM / Piriton
Cetirizine / Zyrtec
Amitriptyline / Elavil
Tianeptine / Coaxil, Stablon
Mirtazapine / Remeron
Quetiapine / Seroquel
Nitrous Oxide / N2O / laughing gas
Amyl Nitrite / Poppers
Ketamine [racemic] / K, Kitty
Esketamine [S-isomer] / Special K
Deschloroketamine / 2'-Oxo-PCM / DCK
N-ethyldeschloroketamine / 2'-Oxo-PCE / O-PCE / Eticyclidone
Deoxymethoxetamine / 3-Me-2′-Oxo-PCE / DMXE
Methoxetamine / 3-MeO-2'-Oxo-PCE / MXE / Mexxy
Hydroxetamine / 3-**-2'-Oxo-PCE / HXE / Hexxy
Methoxpropamine / 2-Oxo-3'-MeO-PCPr / MXPr
Methoxisopropamine / 2-Oxo-3'-MeO-PCiPr / MXiPr
3-Hydroxyphencyclidine / 3-**-***
3-Methoxyphencyclidine / 3-MeO-***
3-Methoxyeticyclidine / 3-MeO-PCE
3-Methyleticyclidine / 3-Me-PCE

Stimulants & Enhancers;
1,3,7-Trimethylxanthine / Caffeine / Coffea, Camellia sinensis / Coffee, Tea
3,7-dimethylxanthine / Theobromine / [constituent of] Chocolate
N-Ethyl-L-glutamine / L-Theanine / [constituent of] Green Tea
Nicotine / Nicotiana / Tobacco, cigarettes, smokes
Ephedrine / Ephedra
Pseudoephedrine / Ephedra, Sudafed
Adrenaline, Epinephrine
Choline bitartrate
L-alpha glycerylphosphorylcholine / Alpha-GPC, Choline alfoscerate
Cytidine 5'-diphosphocholine / CDP-choline, Citicoline
N-Acetylcysteine / NAC
2-Dimethylaminoethyl (4-chlorophenoxy)acetate / Meclofenoxate
N-Phenylacetyl-L-prolylglycine ethyl ester / Omberacetam / Noopept
Coluracetam / BCI-540
4-Phenylpiracetam
Propranolol
(±)-2-Benzhydrylsulfinyleth­anehydroxamic acid / Adrafinil
(±)-2-[(Diphenylmethyl)sulfinyl]acetamide / Modafinil
(–)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide / Armodafinil
α-Methylphenethylamine / Amphetamine, αMP / Speed
N-Methylamphetamine / Methamphetamine / ****
Lisdexamfetamine / Vyvanse, Tyvense, Elvanse
2-Fluoromethamphetamine / 2-FMA
3-Fluoroamphetamine / 3-FA /  PAL-353
4-Fluoroamphetamine / 4-FA, 4-FMP /  PAL-303 / Flux
4-Methoxyamphetamine / PMA, 4-MA / Death
5-Methoxy-2-aminoindane / MEAI, 5-MeO-AI / Chaperone, Pace
Methythiolpropamine / MPA / Blow
3-Fluorophenmetrazine / 3-FPM / PAL-593
Methylphenidate / MPH / Ritalin, Concerta
4-Fluoromethylphenidate / 4F-MPH
4-Fluoroethylphenidate / 4F-EPH
3-Methylmethcathinone / 3-MMC / Metaphedrone
3-Methylethcathinone / 3-MEC
4-Methylmethcathinone / 4-MMC / Mephedrone
4-Methylethcathinone / 4-MEC
3-Chloro-N-tert-butyl-cathinone / Bupropion / Wellbutrin, Zyban
4-Chloromethcathinone / 4-CMC / Clephedrone
4-Fluoromethcathinone / 4-FMC / Flephedrone
4-Fluoro-α-methylaminovalerophenone / 4-Fluoropentedrone / 4-FPD
α-Ethylaminocaprophenone / N-Ethylhexedrone / NEH / Hexen
alpha-Pyrrolidinohexiophenone / α-PHP / PV-7
alpha-Pyrrolidinoisohexaphenone / α-PiHP, α-PHiP
3,4-Methylenedioxy-α-pyrrolidinohexiophenone / MDPHP
3,4-Methyl​enedioxy​pentedrone / βk-MBDP / Pentylone
3,4-Methylenedioxymethcathinone / βk-MDMA / MDMC / Methylone
3,4-Methylenedioxymethamphetamine / MDMA / ecstasy
5-(2-methylaminopropyl)benzofuran / 5-MAPB
6-(2-Aminopropyl)benzofuran / 6-APB / Benzofury
6-(2-Aminopropyl)-2,3-dihydrobenzofuran / 6-APDB / 4-desoxy-MDA
Mesembrine / Sceletium tortuosum, Kanna
Harmine / Peganum harmala / Syrian Rue
3,4,8-Trimethoxyphenanthrene-2,5-diol / Dendrobium nobile
NSI-189
4-chloro-N-(2-morpholin-4-ylethyl)benzamide / Moclobemide
Escitalopram / Cipralex, Lexapro
Fluoxetine / Prozac
Sertraline / Zoloft
Venlafaxine / Effexor
5-Hydroxytryptophan / 5-HTP / Oxitryptan

Hallucinogens & Psychedelics;
Cannabidiol / CBD / Cannabis
Cannabigerol / CBG / Cannabis
Δ9-Tetrahydrocannabinol / THC / Cannabis, Marijuana
Hexahydrocannabinol / HHC
AM-2201 / Synth-'noids, Spice
NM-2201 / CBL-2201
5C-AB-PINICA
Salvinorin A  / Salvia Divinorum / Diviner's Sage
d-Lysergic acid amide / d-Lysergamide / LSA / Ergine
Lysergic acid diethylamide / Lysergide / LSD, LAD / Acid, Lucy
Lysergic acid 2,4-dimethylazetidide / LSZ / Diazedine, Lambda, λ
1-Acetyl-lysergic acid diethylamide / 1A-LSD / ALD-52
1-Propionyl-lysergic acid diethylamide / 1P-LSD
1-Cyclopropionyl-N-Methyl-N-isopropyllysergamide / 1cP-MiPLA
6-Allyl-6-nor-lysergic acid diethylamide / AL-LAD / Aladdin
2,5-Dimethoxy-4-methylamphetamine / DOM / Dominic
2,5-Dimethoxy-4-bromoamphetamine / DOB / Aphrodite
2,5-Dimethoxy-4-chloroamphetamine / DOC / Doctor
2,5-Dimethoxy-4-methylthioamphetamine / DOT / Aleph
2,5-Dimethoxy-4-methyl-α-ethylphenethylamine / 4C-D / Ariadne
2,5-Dimethoxy-4-methylphenethylamine / 2C-D, 2C-M / Matrix
2,5-Dimethoxy-4-ethylphenethylamine / 2C-E / Eternity
2,5-Dimethoxy-4-bromophenethylamine / 2C-B / Nexus
2,5-Dimethoxy-4-chlorophenethylamine / 2C-C / Callisto
2,5-Dimethoxy-4-iodophenethylamine / 2C-I / Infinity
2,5-Dimethoxy-4-methylthiophenethylamine / 2C-T / Tesseract
2,5-Dimethoxy-4-ethylthiophenethylamine / 2C-T-2 / Rosy
2,5-Dimethoxy-4-fluoroethylthiophenethylamine / 2C-T-21 / Aurora
2,5-Dimethoxy-4-bromo-β-keto-phenethylamine / βk-2C-B
2,5-Dimethoxy-4-bromo-β-hydroxy-phenethylamine / βOH-2C-B / BOHB
2,3,6,7-Benzo-dihydro-difuran-8-bromo-ethylamine / 2C-B-FLY
2,5-Dimethoxy-N-(2-methoxybenzyl)-4-bromophenethylamine / 25B
2,5-Dimethoxy-N-(2-methoxybenzyl)-4-chlorophenethylamine / 25C
2,5-Dimethoxy-N-(2-methoxybenzyl)-4-iodophenethylamine / 25I
2,5-Dimethoxy-N-(2-hydroxybenzyl)-4-ethylphenethylamine / 25E-NBOH
3,4-Methylenedioxyamphetamine / MDA / Sass, Sally
3,4,5-Trimethoxyphenethylamine / Mescaline / M
3,5-Dimethoxy-4-ethoxyphenethylamine / Escaline
3,5-Dimethoxy-4-methallyloxyphenethylamine / Methallylescaline / MAL
α-Methyltryptamine / αMT / Indopan
N,N-dimethyltryptamine / DMT / The Spirit
N,N-dipropyltryptamine / DPT / The Light
N,N-Diisopropyltryptamine / DiPT / The Sound
N-Methyl-N-ethyltryptamine / MET / The Colour
N-Methyl-N-propyltryptamine / MPT
N-Ethyl-N-propyltryptamine / EPT
N-Methyl-N-isopropyltryptamine / MiPT / The Touch
4-Hydroxy-dimethyltryptamine / 4-**-DMT / Psilocybe / Psilocin
4-Phosphoryloxy-N,N-dimethyltryptamine / 4-PO-DMT / Psilocybin
4-Acetoxy-dimethyltryptamine / 4-AcO-DMT / Psilacetin
4-Hydroxy-N-methyl-N-ethyltryptamine / 4-**-MET / Metocin
4-Acetoxy-N-methyl-N-ethyltryptamine / 4-AcO-MET / Metacetin
4-Acetyloxy-N,N-dipropyltryptamine / 4-AcO-DPT / Pracetin
4-Acetoxy-N-methyl-N-cyclopropyltryptmine / 4-AcO-McPT
4-Acetoxy-N-methyl-N-isopropyltryptamine / 4-AcO-MiPT / Mipracetin
4-Hydroxy-N-methyl-N-isopropyltryptamine / 4-**-MiPT / Miprocin
5-Methoxy-N,N-dimethyltryptamine / 5-MeO-DMT / The God, The Power
5-Methoxy-N-methethyltryptamine / 5-MeO-MET / The Vision
5-Methoxy-N,N-diallyltryptamine / 5-MeO-DALT / Foxtrot
5-Methoxy-N-diisopropyltryptamine / 5-MeO-DiPT / Foxy
5-Methoxy-N-methyl-N-isopropyltryptamine / 5-MeO-MiPT / Moxy

I thought it right to assess some antidepressants, which philosophers are more inclined to call mood enhancers.
This was during my foray into human enhancement, substances intended to enhance physicality, cognition or mood. Nootropic compounds concern the latter two categories.

The most commonly prescribed mood enhancers are serotonin reuptake inhibitors (SRIs), but it takes over a week for these compounds reach their peak effect.
Thus I approached them with the notion that a limited dosage might point to their character, though  not reveal. These considerations in mind, I set about acquiring a few miscellaneous anti-D's.

Fluoxetine was the first successful selective serotonin re-uptake inhibitor (SSRI), better known by its original brand-name Prozac. Fluoxetine has an acute biological half-life of between 1-3 days. Presence of a trifluoromethyl group on the compound deserves note, I wonder what the presence of electronegative fluorine atoms add to the psychoactive flavor of a compound (subjective effects).
I administered a single dose by mouth, there was some indication of subjective character. Light serotonergic sensations and seemingly benign mood-dampening, there is a ****** towards the positive. Waking headspace relatively uninteresting. Observed hints of oneirogenesis, did not manifest in enough character to be detailed - a sort of vivid, 'pulsive wandering, more pronounced in contrast to its waking character.
Good experiment, interesting results.
Ligand     Ki (nM)   Ki (nM)
Target      Flx            Nflx
SERT        1               19
NET         660           2700
DAT         4180         420
5-HT2A   200           300
5-HT2B    5000         5100
5-HT2C    72.6          91.2
α1             3000         3900
M1            870           1200
M2            2700         4600
M3            1000         760
M4            2900         2600
M5            2700         2200
H1            3250         10000

Sertraline is another popular SSRI, also known by it's original brand-name Zoloft. Sertraline has a variable half-life, on average 26 hours.
It's metabolite, desmethylsertraline, has a half life between 62-104 hours but is a far less potent Serotonin Releasing Agent (SRA).
The presence of two chlorine atoms is interesting. The usual, phenomenal serotonergicity is present and pushing towards the positive.
Some nausea, particularly when hungry (this disappeared after some minestrone soup). Some faintness after physical exertion. This dose did not promote onirogenesis. There was a moment of cognitive distortion when the proportions of a focal object seemed to be growing in-and-out, shifting in size.
Site                 Ki (nM)
SERT              0.15–3.3
NET               420–925
DAT               22–315
5-HT1A       >35,000
5-HT2A          2,207
5-HT2C          2,298
α1A        ­        1900
α1B                 3,500
α1D                 2,500
α2                  477–4,100
D2                  10,700
H1                  24,000
mACh           427–2,100
σ1                   32–57
σ2                   5,297

Escitalopram is an SSRI commonly prescribed for major depression and generalised anxiety. It is the (S)-stereoisomer of citalopram. The biological half-life is of escitalopram is between 27-32 hours.
I administered a dose and thought the phenomenal serotonergicity less apparent than fluoxetine but then gastro-intestinal disturbance was noted, I surmised it has a high affinity for 5-HT2C.
Any oneiric qualities were not readily apparent after a single dose, relatively little visual imagery which is understandable given its lack of affinity for 5-HT2A. I found this to be philosophically interesting. Mood elevation observed in bursts of conversation and as odd sensations, possible mental discomfort.
Ligand,
Recptr     Ki (nM)
SERT       2.5
NET        6,514
5-HT2C   2,531
α1            3,870
M1           1,242
H1           1,973

Venlafaxine is a selective serotonin-norepinephrine reuptake inhibitor (SNRI). Venlafaxine and its metabolites are active for about 11 hours.
Initial subjective effects similar to a very light empathogenic stimulant. Perception of altered attention-span/increased reflexive response; energizing yet paradoxically much yawning.
Ligand,  Vnfx      Dvnfx
Recptr    Ki(nM)  Ki(nM)
SERT  ­    82           40.2
NET       2480        558.4

Tianeptine is a tricyclic antidepressant (TCA) with an unusual mechanism of action. It is an atypical agonist of the μ-opioid receptor and has been described as a (selective) serotonin reuptake enhancer (SRE). It has a short duration as sodium salts [prescribed form] of between 2-4 hours but as sulfate this can be notably extended, some of its metabolites are active for longer than tianeptine itself.
Definitely anxiolytic, quite artificial; possible aphrodisiac. I find its opioid activity dissuading, requires caution.
Site          Ki (nM)
MOR       383–768 (Ki)
                 194 (EC50)
DOR      >10,000 (Ki)
                 37,400 (EC50)
KOR      >10,000 (Ki)
                 100,000 (EC50)
All other transporter/receptor/sub-receptor values are >10,000 (Ki).

Bupropion is a norepinephrine-dopamine reuptake inhibitor (NDRI) with affinity for some nicotinic receptors. Bupropion and its metabolites are active for between 12-36 hours. Interestingly it is a substituted cathinone.
Initial subjective effects similar to a fairly light stimulant. Perception of increased attention-span and improved cognition. It is an onirogen that is neutral in quality, enhancing vivid dreaming (a boon of its nicotinic affinity which is counteracted if the stimulant component impinges on sleep). Completely absent of serotonergicity, curious.
The N-tert-butyl group's effect is most interesting, how it affects metabolism and to what extent ROAs alter pharmacokinetics.
I took 150mg ******, as extended and as instant release (the latter was more pronounced). I thought an altered pharmakinetic profile might result from bypass of hepatic metabolism, so I tried 25mg insufflated and felt as if there was effect that it differed slightly from oral ROAs, but also worried that its metabolic fate is thence unknown (compare to the neurotoxic 3-CMC). What of other bupropiologues,
for example, 3-Methyl-N-tert-butyl-methcathinone? Indeed.
                        Bupropion    R,R-Hydroxybuprpn   Threo-hydrobuprpn
AUC               1                     23.8                                  11.2
Half-life         11 h                 19 h                                 31 h
IC50 (μM)
DAT               0.66                  inactive                          47 (rat)
NET               1.85                   9.9                                  16 (rat)
SERT              inactive          inactive               ­            67 (rat)
α3β4 nic         1.8                   6.5                                   14 (rat)
α4β2 nic         12                     31                                   no data
α1β1γδ nic     7.9                    7.6                                  no data

Moclobemide is a reversible inhibitor of monoamine oxidase A (RIMA), its monoamine oxidase inhibition lasts about 8–10 hours and wears off completely by 24 hours. Inhibiting the decomposition of monoamines (e.g. serotonin, norepinephrine and dopamine) increases their accumulation at an extracellular level. It tends to suppress REM sleep and so it lacks oneirogenic properties.
Feeling of well-being, less constrained by the usual anxieties; openness. Relatively unnoticeable side-effects when diet is carefully managed. Made the mistake of eating a cheese and turkey sandwich (i.e. foodstuff rich in tryptophan/tyramine), indications of serotonergicity later became apparent: feelings of overheating and flushing, slight sweating, racing thoughts and anxious discomfort. A stark reminder of Shulgin's old adage: "there is no casual experiment".
Combination with a select few tryptamines (not 5-MeO-xxT) should be safe, and synergistic (perfect for pharmahuasca); reputed to potentiate GHB. However, generally it is extremely dangerous to combine with serotonergic drugs.

I'm alone here
I'm alone
Would you just stop
WOULD YOU JUST STOP AND LISTEN TO ME!
I'm alone
And I just repeat that again and again and AGAIN
And it always seems to be true
And I keep thinking
I think I think and I THINK
But nothing seems to happen
We're trapped
WE ARE TRAPPED
And yet I'm free to roam
You're free to go
You're free to go just go JUST GO
But I'm running away
From what from who FROM WHERE
Freedom freedom freedom OY
Freedom freedom freedom OY
Quit pestering me
Quit it YOURE NOT EVEN HERE
I wish I could go
I need an adventure
I need to go
GET AWAY FROM ME
Oh god HOW DO THEY DO IT
blank memories
blank thoughts
empty files
empty plot
scared frozen
scared free
scared forever
scared me
Meds meds meds
Drugs drugs brain
Empty clear fuzzy
Gone

She's screaming at me
from the tile floor of the bathroom
and there's sick in her hair
so I just ring her mother.

I'm disgusted at her,
it's pathetic. I'm sick of listening
to this, and holding hair back,
and stuffing my hand down throats
to feel the ***** crawl back up to catch me.

I'm standing in a house in a bad estate
and it's 8AM
and how did I get here?
I left my friend behind in a bathroom
because I can't bare to see her and remember
crying in a nightclub bathroom in Carrick
and not knowing why.

The room is spinning, but at least I'm smiling.
I think this boy is quite pretty, really.
Where is she? Sprawled out, puking
in the sheets of her bed. I'm not sympathetic.
Take your medication you headcase,
we need it to function - just take it, I swear.

Wake up just to go back to sleep
Later I'll take some antidepressants, but this **** ain't cheap
Waiting to feel good, I'll play some DOOM
**** them all in a dark dead room
Life is basically like an illusion
**** it, life's giving me a mental confusion
Time flies and it's already 11 at night
Everything is black and white

so ****** in the face of it
at the end of it, your perception
on the nose of it
this feeling in my nose
this tingling wall
this numby crunchy face on my face that blocks out the light and the truth and the life .... that's how it feels .... sorta
how crazy does that read?
i'll bet it reads ugly.
i'll bet it reads sick.
it should because its a description of drugs crazy people, ie. people like me take to try to feel less crazy
they make your ******* face feel like it jumped rebellious,
eyes, ears, nose, throat, turned traitor.

Escitalopram
Buproin
Nuvigil
Lithium Carbonate
Quetiapine
Abilify
Risperdone
Harpoon IPA
Johnnie Walker Red Label blended scotch whiskey

it seems there can come a certain special kind of time in a man's life,
when he can feel weird and lonely enough
to type a few words
and call it poem.
******* Bukowski.
this is his legacy.  the possibility to do what I'm doing right now.
without that disgusting, self-centered fool
I never would have thought to try and write these weird feelings I'm feeling.

a little attention,
that's what strokes this need.
a few incidental internet readers,
to read this strangely pointless pontification
on the bits of sadness that are me.

i wish i could find an open field
and lay back comfortable
in the crisp cold air
and feel the stars shoot through me
my heart pounding in the dirt
and waiting for *** or sun or wolves or rain
or anything else you might call "love."

i wish for more death
or more life
I can't stay here.

so ****** in the face of it
at the end of it, your perception
on the nose of it
this feeling in my nose
this tingling wall
this numby crunchy face on my face that blocks out the light and the truth and the life .... that's how it feels .... sorta
how crazy does that read?
i'll bet it reads ugly.
i'll bet it reads sick.
it should because its a description of drugs crazy people, ie. people like me take to try to feel less crazy
they make your ******* face feel like it jumped rebellious,
eyes, ears, nose, throat, turned traitor.

Escitalopram
Buproin
Nuvigil
Lithium Carbonate
Quetiapine
Abilify
Risperdone
Harpoon IPA
Johnnie Walker Red Label blended scotch whiskey

it seems there can come a certain special kind of time in a man's life,
when he can feel weird and lonely enough
to type a few words
and call it poem.
******* Bukowski.
this is his legacy.  the possibility to do what I'm doing right now.
without that disgusting, self-centered fool
I never would have thought to try and write these weird feelings I'm feeling.

a little attention,
that's what strokes this need.
a few incidental internet readers,
to read this strangely pointless pontification
on the bits of sadness that are me.

i wish i could find an open field
and lay back comfortable
in the crisp cold air
and feel the stars shoot through me
my heart pounding in the dirt
and waiting for *** or sun or wolves or rain
or anything else you might call "love."

i wish for more death
or more life
I can't stay here.

never rub another man's rhubarb.

so this article comes along
about aya-huskie,
****... what was it?
                              ayahuasca
and i'm reading it,
and i'm reading into it,
and i'm like:
     it's not unusual for 100+
ceremonies ingesting
this drug happen in new york
on a daily basis...
****'s more potent that
corresponding a war...
   the female enegry *madre:
hocus pokus
          harry houdini
       eating a pear as a magic
            trick *******...
nope...
   i'm fine my beer, my love
of home-cooked food,
my music...
       what am i implying?
   the ****'s contaminated -
just like the beatnik poets
contaminated peyote...
contaminated, how?
  they wrote about it...
who the **** is going to moan
and complain about me
writing about drinking?
                           um... no one?
the brew is so abused that
when sometimes comes
along and writes about its
effects, in a positive way:
you don't really start moaning...
all those soppy:
  papa was an alcoholic type
stories...
   mama drank a bottle
of wine before putting me to bed:
too bad *******!
    live with the fact,
that somewhere, somehow,
there's a drunk who could
juggle a monkey, a tambourine
and banana:
  and call it a musical instrument!
you ingest something
for a sense of humour -
or you ingest something for
a sense of wonder...
aya-hoo-haha-caska
   is of the latter category...
alcohol?
            ugh: the former!

and to be honest?
    the only and at the same
time the most spiritual experience
i ever had or will have:
will remain:
          hearing myself laughing.
that's it!

the sort of laugh imitating a fox,
the sort of laugh imitating muttley,
and the laugh that feels
like easing a **** of crunching
the stomach...
      the visionaries can keep their
discontent with dreams,
and experience them wide-awake...

but reading this article is numbing...
always the ******* westerners,
the white "bad boys",
what they'll do with ayahuasca
is what they did with cows, pigs,
dogs and cats...
   they'll domesticate the drug...
oh look... already domesticated
being categorised as a drug, rather
than the original of: medicine...

and that's what western society does...
find me a shaman using
alcohol and i'll find you a pair
of scissors in an ayahuasca experience...
but i just hate the idea
of domesticating something so
spiritually governed...

people really think that taking this
drug, in the centre of new york
will somehow create an actual
organic potency of the drug?
          in new york the experience
will be inorganic -
        and most probably horrific -

well **** me: jump off a roof and
hallucinate a pair torn off icarus!
    up here, in the hinterlands,
in catholic schools,
   they still told us what the ukrainians
used to do: sniff glue
   (can i recommend a film?
    lilya 4-ever) -
       or don't get me strated with poles
drinking purple denaturat,
     (denatonium, methanol -
                         in short? toxins!) -

personall i don't like the idea where
this ahaya ahooya, whatever thing is going...
to me it has a scent of a process
of domestication...
        but i suppose if you're going
to deforest the amazon,
    you also have to attack the spirit -

now that i've read about the experience,
i'm rather keen on trying to
unravel the problem of antidepressants:
also in the same newspaper...
   namely escitalopram (lexarpo)
  & sertraline & clonazepam
  & paroxetine (seroxat) - all of them being
anti-depressants; so no:

i wouldn't disturb the amazonian shamans
for some "bogus" life-changing
experiences, i'd look at the situation where
drugs have moved beyond the stage
of being domesticated from their natural
environment... and... therefore?
                                    industrialised!

talk to random schizophrenic in the middle
of a night over a kalimotxo (basque drink,
red wine and coca-cola - kali kali kali
m'oh ch'oh) -
and he'll tell you: yeah, knew a guy,
was on antipsychotic medication:
                                 grew a pair of ****!

oh yeah, tobacco & alcohol are baaah!
baaah! bad! (please invoke a sheepish
stutter within the confines of the italics).

What a strange Halloween week,
I am underwhelmed, I did not
overindulge, despite the
list of things I ate:
MPA, hash oil, 2C-B,
4-**-MiPT, escitalopram.
My head is not sated, I can feel
a sensation of unanswered cravings;

Xanax is the devil
When mixed with too much drink
And so is escitalopram
That is what I think

    These things conspire to change your vibe
    And now it seems if you imbibe
    The smallest teensy tiny touch
    Of *****, it’s ...still a bit too much...

Seems my Dear has disappeared,
And swaying in her place
Another person, as I feared,
Without the charm; without the grace,

    I cannot stand my latest role:
    Authoritative scolding troll
    And I, not knowing what to do
    Retreat into a deep dark blue

Everything makes me tired
Lithium
Seroquel
Escitalopram
Sertraline
Hydroxyzine
And so far nothing has worked
I constantly feel overwhelmed
Undervalued
And sad
This Pandemic has devoured my paycheck
And I have learned how
Unimportant I am in such an oversaturated market
My brain feels so scattered and
It does not feel like my birthday
After all what is there to celebrate
By my own actions and choices I have no friends
My medications cause outbursts of anger
And my soon to be husband gets the short end of that stick
I am a mess and I am full of missing

Sit across the psychologist,
and wait as they assess how to fix you.

Ignore the persistent buzzing from the ceiling, keyboard clacking,
box of what seems to be sedatives - just in case this goes wrong.

Pretend that you're having friendly conversation,
all while insides fail and you wonder if you'll make it to the end.

Tell them all the deepest darkest secrets,
those that you wouldn't dare whisper even to yourself at night.

Notice how they watch you with a critical eye,
picking you apart and laying out the pieces of yourself.

Don't flinch as they crudely collect the most painful parts,
for that just shows that theres still some left in you.

Don't whimper in grief as they discard of these ragged fragments,
dropping in a solution of escitalopram and hollow affirmations.

Don't notice how this left you with was an empty sort of numbness,
it's just apart of the process.

Don't tell them that of the shards still left wounds,
because it'll scar over and heal in (a long long interminable) time.

Don't mention how you still don't feel okay,
because then you must just be doing it wrong.

Don't tell them how you're still not, and will possibly never be okay,
Don't tell them that those shards are only growing,
Don't tell them that you're empty,
Don't tell them that you sort of miss the insisting hurt,
Don't tell them how you are simply not capable of being "okay",

because then they'll have to take more drastic measures.
Anything to help you get "better".